ID   FRAC_NOSS1              Reviewed;         179 AA.
AC   P46078;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Filament integrity protein FraC;
GN   Name=fraC; OrderedLocusNames=alr2392;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7883709; DOI=10.1128/jb.177.6.1520-1526.1995;
RA   Bauer C.C., Buikema W.J., Black K., Haselkorn R.;
RT   "A short-filament mutant of Anabaena sp. strain PCC 7120 that fragments in
RT   nitrogen-deficient medium.";
RL   J. Bacteriol. 177:1520-1526(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Involved in filament integrity. Required for the integrity of
CC       cell junctions in general but is apparently not directly involved in
CC       normal differentiation and nitrogen fixation.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; S76266; AAB33741.1; -; Genomic_DNA.
DR   EMBL; U09240; AAA18029.1; -; Unassigned_DNA.
DR   EMBL; BA000019; BAB74091.1; -; Genomic_DNA.
DR   PIR; AI2104; AI2104.
DR   RefSeq; WP_010996548.1; NZ_RSCN01000002.1.
DR   AlphaFoldDB; P46078; -.
DR   SMR; P46078; -.
DR   STRING; 103690.17131484; -.
DR   TCDB; 1.V.1.1.1; the filamentous cyanobacterial septal pore (septum) family.
DR   EnsemblBacteria; BAB74091; BAB74091; BAB74091.
DR   KEGG; ana:alr2392; -.
DR   eggNOG; ENOG503312T; Bacteria.
DR   OMA; TFLMKFF; -.
DR   OrthoDB; 2036326at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..179
FT                   /note="Filament integrity protein FraC"
FT                   /id="PRO_0000087330"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   179 AA;  21040 MW;  0DE248AA814BAC76 CRC64;
     MFEDLTIPRI WPIGAILFNL LFLLIAIPIE GYIYHRRLNF DKKTSIFYAI AVNSFSGVIG
     WVIFFFVEPV LPVPIKAELI NYIFFNIFRS TNTQGVLIFT TFIIFFSTFL MKFFLLRLFV
     FTLSEDIGKK QEEPQPFYRQ KVRFISRIRL QDTNLVTTTL IANSLSYTAI TIILLIRNR