ID   FRAH_NOSS1              Reviewed;         289 AA.
AC   P46017;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Protein FraH;
GN   Name=fraH; OrderedLocusNames=alr1603;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RA   Bauer C.C., Scappino L., Haselkorn R.;
RT   "Bacterial subtracted cDNA libraries containing genes involved in the
RT   differentiation of vegetative cells to heterocysts allow a new twist on an
RT   old method of isolating developmental genes.";
RL   Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Putative heterocyst to vegetative cell connection.
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DR   EMBL; U14553; AAA50356.1; -; Genomic_DNA.
DR   EMBL; BA000019; BAB77969.1; -; Genomic_DNA.
DR   PIR; AE2006; AE2006.
DR   RefSeq; WP_010995772.1; NZ_RSCN01000041.1.
DR   AlphaFoldDB; P46017; -.
DR   SMR; P46017; -.
DR   STRING; 103690.17135423; -.
DR   EnsemblBacteria; BAB77969; BAB77969; BAB77969.
DR   KEGG; ana:alr1603; -.
DR   eggNOG; COG1716; Bacteria.
DR   OMA; AAFCGQC; -.
DR   OrthoDB; 1632705at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043158; P:heterocyst differentiation; IEA:UniProtKB-KW.
DR   CDD; cd00060; FHA; 1.
DR   InterPro; IPR025874; DZR.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   Pfam; PF12773; DZR; 1.
DR   Pfam; PF00498; FHA; 1.
DR   SMART; SM00240; FHA; 1.
DR   SUPFAM; SSF49879; SSF49879; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
PE   4: Predicted;
KW   Heterocyst; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..289
FT                   /note="Protein FraH"
FT                   /id="PRO_0000087331"
FT   DOMAIN          204..260
FT                   /note="FHA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00086"
FT   ZN_FING         4..49
FT                   /note="DZANK-type"
FT                   /evidence="ECO:0000255"
FT   ZN_FING         18..48
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   289 AA;  29922 MW;  47C9091E50B39716 CRC64;
     MIVCPNCNHP NPDGAVQCEA CYTPLPATSN CPNCGATVQS DAAFCGQCGF NLHSVAAPAA
     TVATIAPDVP VEVPPLANPD PLLELLQPNA LGLDPVANEN PPAPAPLPPT AVAAPPDATP
     VVVEVTPAPP PPEPVVVEAS IPTPPPEPVA PPEPVPAVEP APAPETVVAA PPSPARTQLQ
     QITARLVHVQ SDQEIELPPS LSVVHIGKPN DRIPPDVDVS GFANSEIVSR VHADIRLEGD
     AHYIEDVGSS NGTYINNLPL LPGNRHRLRP GDRISLGKGD LVTFLFKLA