FRIG0_ARATH
ID FRIG0_ARATH Reviewed; 314 AA.
AC Q67Z93; O65274; Q9FDW0;
DT 25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=Inactive protein FRIGIDA;
GN Name=FRI; OrderedLocusNames=At4g00650; ORFNames=F6N23.25;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the Frigida family. {ECO:0000305}.
CC -!- CAUTION: In strain cv. Columbia, cv. Landsberg Erecta and cv.
CC Wassilewskija, loss-of-function mutations lead to inactive FRI protein.
CC A complete sequence for FRI can be found in strains cv. H51 (AC
CC P0DH90). {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC13626.1; Type=Erroneous gene model prediction; Note=In cv. Columbia, the gene is defective and the CDS could not be predicted correctly.; Evidence={ECO:0000305};
CC Sequence=CAB80874.1; Type=Erroneous gene model prediction; Note=In cv. Columbia, the gene is defective and the CDS could not be predicted correctly.; Evidence={ECO:0000305};
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DR EMBL; AF058919; AAC13626.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161472; CAB80874.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE81913.1; -; Genomic_DNA.
DR EMBL; AK176173; BAD43936.1; -; mRNA.
DR EMBL; AK176225; BAD43988.1; -; mRNA.
DR RefSeq; NP_567181.2; NM_116290.4.
DR AlphaFoldDB; Q67Z93; -.
DR SMR; Q67Z93; -.
DR BioGRID; 13335; 11.
DR STRING; 3702.AT4G00650.1; -.
DR PaxDb; Q67Z93; -.
DR PRIDE; Q67Z93; -.
DR EnsemblPlants; AT4G00650.1; AT4G00650.1; AT4G00650.
DR GeneID; 828044; -.
DR Gramene; AT4G00650.1; AT4G00650.1; AT4G00650.
DR KEGG; ath:AT4G00650; -.
DR Araport; AT4G00650; -.
DR TAIR; locus:2127013; AT4G00650.
DR eggNOG; ENOG502QUHP; Eukaryota.
DR HOGENOM; CLU_064590_0_0_1; -.
DR InParanoid; Q67Z93; -.
DR OMA; ADFLDQW; -.
DR OrthoDB; 1152213at2759; -.
DR PRO; PR:Q67Z93; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q67Z93; baseline and differential.
DR Genevisible; Q67Z93; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0046982; F:protein heterodimerization activity; IPI:TAIR.
DR GO; GO:0042803; F:protein homodimerization activity; IPI:TAIR.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0009910; P:negative regulation of flower development; IMP:TAIR.
DR GO; GO:0048510; P:regulation of timing of transition from vegetative to reproductive phase; IMP:TAIR.
DR GO; GO:0010321; P:regulation of vegetative phase change; IMP:TAIR.
DR GO; GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
DR InterPro; IPR012474; Frigida.
DR Pfam; PF07899; Frigida; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Developmental protein; Differentiation; Flowering; Nucleus;
KW Reference proteome.
FT CHAIN 1..314
FT /note="Inactive protein FRIGIDA"
FT /id="PRO_0000415341"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 67..97
FT /evidence="ECO:0000255"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 34973 MW; 2F9C00EB52D644CD CRC64;
MSNYPPTVAA QPTTTANPLL QRHQSEQRRR ELPKIVETES TSMDITIGQS KQPQFLKSID
ELAAFSVAVE TFKRQFDDLQ KHIESIENAI DSKLESNGVV LAARNNNFHQ PMLSPPRNNV
SVETTVTVSQ PSQEIVPETS NKPEGERICE LMCSKGLRKY IYANISDQAK LMEEIPSALK
LAKEPAKFVL DCIGKFYLQG RRAFTKESPM SSARQVSLLI LESFLLMPDR GKGKVKIESW
IKDEAETAAV AWRKRLMTEG GLAAAEKMDA RGLLLLVACF GVPSNFRSTD LLDLIRMSGS
NEIAGALKRS QFQV
