FRL3_ARATH
ID FRL3_ARATH Reviewed; 558 AA.
AC Q67ZB3; Q8L7D6; Q9LV73;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=FRIGIDA-like protein 3;
GN Name=FRL3; OrderedLocusNames=At5g48385; ORFNames=MJE7.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=14973192; DOI=10.1073/pnas.0306778101;
RA Michaels S.D., Bezerra I.C., Amasino R.M.;
RT "FRIGIDA-related genes are required for the winter-annual habit in
RT Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:3281-3285(2004).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=20405310; DOI=10.1007/s11103-010-9635-2;
RA Risk J.M., Laurie R.E., Macknight R.C., Day C.L.;
RT "FRIGIDA and related proteins have a conserved central domain and family
RT specific N- and C- terminal regions that are functionally important.";
RL Plant Mol. Biol. 73:493-505(2010).
CC -!- INTERACTION:
CC Q67ZB3; Q940H8: FRL4B; NbExp=3; IntAct=EBI-4440511, EBI-4442126;
CC -!- SIMILARITY: Belongs to the Frigida family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA96959.1; Type=Erroneous gene model prediction; Note=The predicted gene At5g48390 has been split into 2 genes: At5g48385 and At5g48390.; Evidence={ECO:0000305};
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DR EMBL; AB020745; BAA96959.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED95663.1; -; Genomic_DNA.
DR EMBL; AY136326; AAM96992.1; -; mRNA.
DR EMBL; BT000104; AAN15423.1; -; mRNA.
DR EMBL; AK176205; BAD43968.1; -; mRNA.
DR EMBL; AK226356; BAE98504.1; -; mRNA.
DR EMBL; AK230331; BAF02130.1; -; mRNA.
DR RefSeq; NP_850923.1; NM_180592.3.
DR AlphaFoldDB; Q67ZB3; -.
DR SMR; Q67ZB3; -.
DR BioGRID; 20139; 9.
DR IntAct; Q67ZB3; 9.
DR STRING; 3702.AT5G48385.1; -.
DR iPTMnet; Q67ZB3; -.
DR PaxDb; Q67ZB3; -.
DR PRIDE; Q67ZB3; -.
DR ProteomicsDB; 228950; -.
DR EnsemblPlants; AT5G48385.1; AT5G48385.1; AT5G48385.
DR GeneID; 834893; -.
DR Gramene; AT5G48385.1; AT5G48385.1; AT5G48385.
DR KEGG; ath:AT5G48385; -.
DR Araport; AT5G48385; -.
DR TAIR; locus:1005716104; AT5G48385.
DR eggNOG; ENOG502RRHA; Eukaryota.
DR HOGENOM; CLU_026883_2_1_1; -.
DR OMA; FYASRMT; -.
DR OrthoDB; 1100563at2759; -.
DR PhylomeDB; Q67ZB3; -.
DR PRO; PR:Q67ZB3; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q67ZB3; baseline and differential.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR InterPro; IPR012474; Frigida.
DR Pfam; PF07899; Frigida; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Developmental protein; Differentiation; Flowering;
KW Reference proteome.
FT CHAIN 1..558
FT /note="FRIGIDA-like protein 3"
FT /id="PRO_0000423742"
FT REGION 454..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 9..102
FT /evidence="ECO:0000255"
FT COMPBIAS 477..492
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 453
FT /note="K -> E (in Ref. 3; AAM96992/AAN15423)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 558 AA; 62615 MW; EB273B77714F99BC CRC64;
MEDTRSVASL MDSTSSKIQQ LQKAFAELES QRAVTLNLKW KELEEHFHGL ERSLKRRFHE
LEDQEKEYET KTRKAQELLE KKKAAVEAKE KAALERLQKK RDAAMFTINS ALDKYNNAPV
SKPSVGERWP QNAVEDSSNV FAADSITDDN PDGIVQDVQI SPVMGNYEVK AYPQLLKLCG
DMDSTGLHKF VSDNRKNLAS LKEEIPMAFR AAANPASLVL DSLEGFYPME APTADGKKDA
NLLGMRRTCI MLMECLSILL SGLDRNCLAV VLSQNVKHRA KTIAEGWNPL LESLDMDACN
GNSLEAHAFL QLLATFAIVA DFKEDELLKL IPMVSRRRQA AELCRSLGLA EKMPGVIEVL
VNSGKQIDAV NLAFAFELTE QFSPVSLLKS YLIEARRSSP QGRPGNASPA VQDEFNEREL
IGLKTVIKCI EEHSLEEQYP VEPLHKRILQ LEKAKADKKR ATEPMKPQPK RPRGAQPRVT
DNNNNINNNK TGYGRVIPER YPQYVYDNRP FLSGPIMAAQ PPPPPPPQTY TFNPAPAHGN
FYANCYQYQA PPPPPYFH
