ID   FRL4A_ARATH             Reviewed;         532 AA.
AC   Q9LUV4;
DT   16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=FRIGIDA-like protein 4a;
GN   Name=FRL4A; OrderedLocusNames=At3g22440; ORFNames=MCB17.20;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY.
RX   PubMed=14973192; DOI=10.1073/pnas.0306778101;
RA   Michaels S.D., Bezerra I.C., Amasino R.M.;
RT   "FRIGIDA-related genes are required for the winter-annual habit in
RT   Arabidopsis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:3281-3285(2004).
RN   [6]
RP   GENE FAMILY, NOMENCLATURE, AND TISSUE SPECIFICITY.
RX   PubMed=20405310; DOI=10.1007/s11103-010-9635-2;
RA   Risk J.M., Laurie R.E., Macknight R.C., Day C.L.;
RT   "FRIGIDA and related proteins have a conserved central domain and family
RT   specific N- and C- terminal regions that are functionally important.";
RL   Plant Mol. Biol. 73:493-505(2010).
CC   -!- TISSUE SPECIFICITY: Expressed in leaves, shoot apex, flowers and during
CC       seed development. {ECO:0000269|PubMed:20405310}.
CC   -!- SIMILARITY: Belongs to the Frigida family. {ECO:0000305}.
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DR   EMBL; AB022215; BAB01784.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE76640.1; -; Genomic_DNA.
DR   EMBL; AY050770; AAK92705.1; -; mRNA.
DR   EMBL; AY096625; AAM20275.1; -; mRNA.
DR   EMBL; AY085142; AAM61695.1; -; mRNA.
DR   RefSeq; NP_566709.1; NM_113143.3.
DR   AlphaFoldDB; Q9LUV4; -.
DR   SMR; Q9LUV4; -.
DR   BioGRID; 7147; 17.
DR   IntAct; Q9LUV4; 18.
DR   STRING; 3702.AT3G22440.1; -.
DR   PaxDb; Q9LUV4; -.
DR   PRIDE; Q9LUV4; -.
DR   ProteomicsDB; 228944; -.
DR   EnsemblPlants; AT3G22440.1; AT3G22440.1; AT3G22440.
DR   GeneID; 821815; -.
DR   Gramene; AT3G22440.1; AT3G22440.1; AT3G22440.
DR   KEGG; ath:AT3G22440; -.
DR   Araport; AT3G22440; -.
DR   TAIR; locus:2087872; AT3G22440.
DR   eggNOG; ENOG502QVU4; Eukaryota.
DR   HOGENOM; CLU_026883_3_0_1; -.
DR   InParanoid; Q9LUV4; -.
DR   OMA; SFCVKMD; -.
DR   OrthoDB; 679110at2759; -.
DR   PhylomeDB; Q9LUV4; -.
DR   PRO; PR:Q9LUV4; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LUV4; baseline and differential.
DR   Genevisible; Q9LUV4; AT.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR   InterPro; IPR012474; Frigida.
DR   Pfam; PF07899; Frigida; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Differentiation; Flowering; Reference proteome.
FT   CHAIN           1..532
FT                   /note="FRIGIDA-like protein 4a"
FT                   /id="PRO_0000423743"
FT   REGION          406..432
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   532 AA;  59229 MW;  8E888B066A339B04 CRC64;
     MGSVPDPGEL TELAQPSFEE FQKQTSLMTS CTLLWQELSD HFTSLEQNLM KKSEALKQMI
     ETLDNQTQTS LESLKRREVT IDHSVEIVAG KVGERARAAL ESLEKARDGC GDGSNDDSGD
     VDDEEGLLSA LKSLCLKMDA RGFWNFVTAR KKELENLRSK IPAALVDCVD PAMLVLEAIS
     EVFPVDTRGD KVSNDYGWAC VVILESLTPV IVDPVIGKSR LLVTPSVKEK AKEIAETWKK
     SLEERGRIEN VKTPDVHTFL QHLVTFGIVK SEDLALYRKL VVGSAWRKQM PKLAVSVGLG
     DQMPDMIEEL ISRGQQLDAV HFTYEVGLVD KFPPVPLLKA YLRDAKKSAA SIMEDSSNTG
     RATHLVARKE QSALKAVLKC IEEYKLEEEF PPENLKKRLD QLEKTKTEKR KPAAVPANKR
     TRASYNGPMP PAKAGRITNA YVSSFPFIRS PSHSPQYASP AAYPSPPTTV YSNRSPPYPY
     SPEIIPGSYQ GSPIGYPAYN GYCNGPVPAP APPVYHPHHH QHHQFHHQQH YY