FRL4B_ARATH
ID FRL4B_ARATH Reviewed; 532 AA.
AC Q940H8; Q8W4S7;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=FRIGIDA-like protein 4b;
GN Name=FRL4B; OrderedLocusNames=At4g14900; ORFNames=dl3490c, FCAALL.410;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=14973192; DOI=10.1073/pnas.0306778101;
RA Michaels S.D., Bezerra I.C., Amasino R.M.;
RT "FRIGIDA-related genes are required for the winter-annual habit in
RT Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:3281-3285(2004).
RN [6]
RP GENE FAMILY, NOMENCLATURE, AND TISSUE SPECIFICITY.
RX PubMed=20405310; DOI=10.1007/s11103-010-9635-2;
RA Risk J.M., Laurie R.E., Macknight R.C., Day C.L.;
RT "FRIGIDA and related proteins have a conserved central domain and family
RT specific N- and C- terminal regions that are functionally important.";
RL Plant Mol. Biol. 73:493-505(2010).
CC -!- INTERACTION:
CC Q940H8; Q67ZB3: FRL3; NbExp=3; IntAct=EBI-4442126, EBI-4440511;
CC -!- TISSUE SPECIFICITY: Expressed in leaves, shoot apex, flowers and during
CC seed development. {ECO:0000269|PubMed:20405310}.
CC -!- SIMILARITY: Belongs to the Frigida family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL31182.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AL117321; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002687; AEE83517.1; -; Genomic_DNA.
DR EMBL; AY054618; AAK96809.1; -; mRNA.
DR EMBL; AY081543; AAM10105.1; -; mRNA.
DR EMBL; AY060551; AAL31182.1; ALT_INIT; mRNA.
DR EMBL; AY086472; AAM63474.1; -; mRNA.
DR RefSeq; NP_567447.1; NM_117576.3.
DR AlphaFoldDB; Q940H8; -.
DR SMR; Q940H8; -.
DR BioGRID; 12444; 10.
DR IntAct; Q940H8; 10.
DR STRING; 3702.AT4G14900.1; -.
DR PaxDb; Q940H8; -.
DR PRIDE; Q940H8; -.
DR EnsemblPlants; AT4G14900.1; AT4G14900.1; AT4G14900.
DR GeneID; 827147; -.
DR Gramene; AT4G14900.1; AT4G14900.1; AT4G14900.
DR KEGG; ath:AT4G14900; -.
DR Araport; AT4G14900; -.
DR TAIR; locus:2130429; AT4G14900.
DR eggNOG; ENOG502QVU4; Eukaryota.
DR HOGENOM; CLU_026883_3_0_1; -.
DR InParanoid; Q940H8; -.
DR OMA; HHIQHAY; -.
DR OrthoDB; 679110at2759; -.
DR PhylomeDB; Q940H8; -.
DR PRO; PR:Q940H8; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q940H8; baseline and differential.
DR Genevisible; Q940H8; AT.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR InterPro; IPR012474; Frigida.
DR Pfam; PF07899; Frigida; 1.
PE 1: Evidence at protein level;
KW Developmental protein; Differentiation; Flowering; Reference proteome.
FT CHAIN 1..532
FT /note="FRIGIDA-like protein 4b"
FT /id="PRO_0000423744"
SQ SEQUENCE 532 AA; 59364 MW; C7257E0AC1CE9B40 CRC64;
MESSPDPGEL IKSSQPSFFE FQKQASLMTS CNLLWKELSE HFTSMEQNLM KKSEALRQMI
ETLDNQTQSS IELLKHREVT IDHSVEIAEG KVEERVRAAL DSLEKARDCG DEDTGEVDDG
DGLLSALKSL CLKMDARGFW GFVIARKKEL ENLRSQIPVA LVDCVDPPKL VLEAVSEVFP
VDKRGGGEKV SNDFGWACVV ILESLIPVMV DPVMGKSRLL VTPSVKEKAK EIAETWKASL
EERGGIENVK TPDVHTFLQH LVTFGIVKKD DLALYRKLVV GSAWRKQMPK LAVSVGLGDQ
MPDMIEELII RGQQLDAVHF TFEVGLVHLF PPVPLLKAYL RDAKKATALI TDDSNNSGRS
AHLVARKEQS ALRAVLKCIE EYKLEEEFPP ENLKKRLDQL EKTKTEKRKP AVIPANKRTR
ASYSGPMPPA KAGRITNAYV SSFPPPPPTF IRSQSHSPQY GVPAYTTSPP TIYSNRSPPY
QYSPEAVHGS YQTSPVSYPT AYGTYCSPVA APPPPVYHPH PHHHHHIQHA YY
