ID   FRMB_DICDI              Reviewed;         478 AA.
AC   Q55E74;
DT   09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=FERM domain-containing protein B;
GN   Name=frmB; ORFNames=DDB_0190205, DDB_G0269362;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000005; EAL72031.1; -; Genomic_DNA.
DR   RefSeq; XP_645907.1; XM_640815.1.
DR   AlphaFoldDB; Q55E74; -.
DR   SMR; Q55E74; -.
DR   STRING; 44689.DDB0233516; -.
DR   PaxDb; Q55E74; -.
DR   EnsemblProtists; EAL72031; EAL72031; DDB_G0269362.
DR   GeneID; 8616848; -.
DR   KEGG; ddi:DDB_G0269362; -.
DR   dictyBase; DDB_G0269362; frmB.
DR   eggNOG; KOG4229; Eukaryota.
DR   HOGENOM; CLU_571660_0_0_1; -.
DR   InParanoid; Q55E74; -.
DR   OMA; NYPCEED; -.
DR   PRO; PR:Q55E74; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0005829; C:cytosol; TAS:dictyBase.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0010810; P:regulation of cell-substrate adhesion; IMP:dictyBase.
DR   GO; GO:0031156; P:regulation of sorocarp development; IMP:dictyBase.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   Pfam; PF00373; FERM_M; 1.
DR   SMART; SM00295; B41; 1.
DR   SUPFAM; SSF47031; SSF47031; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS50057; FERM_3; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..478
FT                   /note="FERM domain-containing protein B"
FT                   /id="PRO_0000391332"
FT   DOMAIN          48..468
FT                   /note="FERM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00084"
FT   REGION          19..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          129..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          202..221
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        129..190
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   478 AA;  53364 MW;  99D1BD27E0FF1FD8 CRC64;
     MESSFEASKS LNENRDDIEL IPTQSQGSPS LSSSSTITST SRLGSNQVLI RIYFIDDTHK
     TLSIDPNNTT GDQLWEMVSE KLGINNRDSE CFFVWAQNDE IEWLLFNHQN ISEVIKNWGI
     LKKRYCNTEE NSPSSSTSSP ILSGLSSIRG KKSNASSTSN ANDGSGSGSG SGSGSGSGSG
     TSTPNSPKGG LSGFLTLGRK NKAQSPQLQS QSSSLSTTIA SEHASKLRSS FPTLGEEGQF
     RLVYRPTSVL PLELERSINT AEATHLFYIQ AIHNVINSNY PCEEDVALKL ASIQLQVLVG
     DQKMEHQDHF KESISRYIPS HLLSKRKAEE WEQLVIPQHS LLRGSDSLQL KRAYLETCQR
     WAYYGSTFFK AKYIPANTSF FTQEFQGKVS IGINGNGFHI IDPKEMKMVS YSYRDIIAWD
     STSNSFTIKF KIGQDKKFET KPYIFKTPQG ELINDLISDW SEEWESKEKK NNKDSKKK