ID   FRMR_ECO57              Reviewed;          91 AA.
AC   Q8X5J3; Q7AH44;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Transcriptional repressor FrmR;
GN   Name=frmR; OrderedLocusNames=Z0457, ECs0412;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Repressor of the frmRAB operon. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FrmR/RcnR family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG54708.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=BAB33835.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE005174; AAG54708.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BA000007; BAB33835.1; ALT_INIT; Genomic_DNA.
DR   PIR; D90680; D90680.
DR   PIR; E64763; E64763.
DR   PIR; H85530; H85530.
DR   RefSeq; NP_308439.4; NC_002695.1.
DR   RefSeq; WP_001141271.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8X5J3; -.
DR   SMR; Q8X5J3; -.
DR   STRING; 155864.EDL933_0419; -.
DR   EnsemblBacteria; AAG54708; AAG54708; Z0457.
DR   EnsemblBacteria; BAB33835; BAB33835; ECs_0412.
DR   GeneID; 67416561; -.
DR   GeneID; 914514; -.
DR   KEGG; ece:Z0457; -.
DR   KEGG; ecs:ECs_0412; -.
DR   PATRIC; fig|386585.9.peg.507; -.
DR   eggNOG; COG1937; Bacteria.
DR   HOGENOM; CLU_130332_3_0_6; -.
DR   OMA; DCGPILQ; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProt.
DR   Gene3D; 1.20.58.1000; -; 1.
DR   InterPro; IPR003735; Metal_Tscrpt_repr.
DR   InterPro; IPR038390; Metal_Tscrpt_repr_sf.
DR   PANTHER; PTHR33677; PTHR33677; 1.
DR   Pfam; PF02583; Trns_repr_metal; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..91
FT                   /note="Transcriptional repressor FrmR"
FT                   /id="PRO_0000340124"
SQ   SEQUENCE   91 AA;  10318 MW;  23305017AAB2C22D CRC64;
     MPSTPEEKKK VLTRVRRIRG QIDALERSLE GDAECRAILQ QIAAVRGAAN GLMAEVLESH
     IRETFDRNDC YSREVSQSVD DTIELVRAYL K