FRMR_ECOK1
ID FRMR_ECOK1 Reviewed; 91 AA.
AC A1A836;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 2.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Transcriptional repressor FrmR;
GN Name=frmR; OrderedLocusNames=Ecok1_03320; ORFNames=APECO1_1644;
OS Escherichia coli O1:K1 / APEC.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=405955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17293413; DOI=10.1128/jb.01726-06;
RA Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J.,
RA Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.;
RT "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7
RT shares strong similarities with human extraintestinal pathogenic E. coli
RT genomes.";
RL J. Bacteriol. 189:3228-3236(2007).
CC -!- FUNCTION: Repressor of the frmRAB operon. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FrmR/RcnR family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABI99825.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000468; ABI99825.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_001141271.1; NC_008563.1.
DR AlphaFoldDB; A1A836; -.
DR SMR; A1A836; -.
DR EnsemblBacteria; ABI99825; ABI99825; APECO1_1644.
DR GeneID; 67416561; -.
DR KEGG; ecv:APECO1_1644; -.
DR HOGENOM; CLU_130332_3_0_6; -.
DR Proteomes; UP000008216; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProt.
DR Gene3D; 1.20.58.1000; -; 1.
DR InterPro; IPR003735; Metal_Tscrpt_repr.
DR InterPro; IPR038390; Metal_Tscrpt_repr_sf.
DR PANTHER; PTHR33677; PTHR33677; 1.
DR Pfam; PF02583; Trns_repr_metal; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Repressor; Transcription; Transcription regulation.
FT CHAIN 1..91
FT /note="Transcriptional repressor FrmR"
FT /id="PRO_0000340125"
SQ SEQUENCE 91 AA; 10318 MW; 23305017AAB2C22D CRC64;
MPSTPEEKKK VLTRVRRIRG QIDALERSLE GDAECRAILQ QIAAVRGAAN GLMAEVLESH
IRETFDRNDC YSREVSQSVD DTIELVRAYL K