ID   FRMR_ECOSM              Reviewed;          91 AA.
AC   B1LIP2;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Transcriptional repressor FrmR;
GN   Name=frmR; OrderedLocusNames=EcSMS35_0388;
OS   Escherichia coli (strain SMS-3-5 / SECEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=439855;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SMS-3-5 / SECEC;
RX   PubMed=18708504; DOI=10.1128/jb.00661-08;
RA   Fricke W.F., Wright M.S., Lindell A.H., Harkins D.M., Baker-Austin C.,
RA   Ravel J., Stepanauskas R.;
RT   "Insights into the environmental resistance gene pool from the genome
RT   sequence of the multidrug-resistant environmental isolate Escherichia coli
RT   SMS-3-5.";
RL   J. Bacteriol. 190:6779-6794(2008).
CC   -!- FUNCTION: Repressor of the frmRAB operon. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FrmR/RcnR family. {ECO:0000305}.
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DR   EMBL; CP000970; ACB16680.1; -; Genomic_DNA.
DR   RefSeq; WP_001141271.1; NC_010498.1.
DR   AlphaFoldDB; B1LIP2; -.
DR   SMR; B1LIP2; -.
DR   EnsemblBacteria; ACB16680; ACB16680; EcSMS35_0388.
DR   GeneID; 67416561; -.
DR   KEGG; ecm:EcSMS35_0388; -.
DR   HOGENOM; CLU_130332_3_0_6; -.
DR   OMA; DCGPILQ; -.
DR   Proteomes; UP000007011; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProt.
DR   Gene3D; 1.20.58.1000; -; 1.
DR   InterPro; IPR003735; Metal_Tscrpt_repr.
DR   InterPro; IPR038390; Metal_Tscrpt_repr_sf.
DR   PANTHER; PTHR33677; PTHR33677; 1.
DR   Pfam; PF02583; Trns_repr_metal; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..91
FT                   /note="Transcriptional repressor FrmR"
FT                   /id="PRO_0000340121"
SQ   SEQUENCE   91 AA;  10318 MW;  23305017AAB2C22D CRC64;
     MPSTPEEKKK VLTRVRRIRG QIDALERSLE GDAECRAILQ QIAAVRGAAN GLMAEVLESH
     IRETFDRNDC YSREVSQSVD DTIELVRAYL K