FRS1_ARATH
ID FRS1_ARATH Reviewed; 687 AA.
AC Q5UBY2; O49426;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 07-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Protein FAR1-RELATED SEQUENCE 1;
GN Name=FRS1; OrderedLocusNames=At4g19990; ORFNames=F18F4.90;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, SUBCELLULAR LOCATION, GENE
RP FAMILY, AND NOMENCLATURE.
RX PubMed=15591448; DOI=10.1104/pp.104.052191;
RA Lin R., Wang H.;
RT "Arabidopsis FHY3/FAR1 gene family and distinct roles of its members in
RT light control of Arabidopsis development.";
RL Plant Physiol. 136:4010-4022(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Putative transcription activator involved in regulating light
CC control of development.
CC -!- INTERACTION:
CC Q5UBY2; Q9SWG3: FAR1; NbExp=3; IntAct=EBI-625440, EBI-625464;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15591448}. Note=The
CC nuclear localization is independent of the light treatment.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q5UBY2-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Expressed in rosette and cauline leaves,
CC inflorescences stems, flowers and siliques.
CC {ECO:0000269|PubMed:15591448}.
CC -!- SIMILARITY: Belongs to the FHY3/FAR1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA16607.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB78999.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY763412; AAV33403.1; -; mRNA.
DR EMBL; AL021637; CAA16607.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161552; CAB78999.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; T04883; T04883.
DR AlphaFoldDB; Q5UBY2; -.
DR IntAct; Q5UBY2; 1.
DR STRING; 3702.AT4G19990.2; -.
DR PaxDb; Q5UBY2; -.
DR PRIDE; Q5UBY2; -.
DR ProteomicsDB; 228953; -. [Q5UBY2-1]
DR EnsemblPlants; AT4G19990.3; AT4G19990.3; AT4G19990.
DR Gramene; AT4G19990.3; AT4G19990.3; AT4G19990.
DR Araport; AT4G19990; -.
DR eggNOG; ENOG502QQDK; Eukaryota.
DR InParanoid; Q5UBY2; -.
DR PhylomeDB; Q5UBY2; -.
DR PRO; PR:Q5UBY2; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q5UBY2; baseline and differential.
DR Genevisible; Q5UBY2; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR004330; FAR1_DNA_bnd_dom.
DR InterPro; IPR031052; FHY3/FAR1.
DR InterPro; IPR006564; Znf_PMZ.
DR InterPro; IPR007527; Znf_SWIM.
DR PANTHER; PTHR31669; PTHR31669; 2.
DR Pfam; PF03101; FAR1; 1.
DR Pfam; PF04434; SWIM; 1.
DR SMART; SM00575; ZnF_PMZ; 1.
DR PROSITE; PS50966; ZF_SWIM; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Coiled coil; Metal-binding; Nucleus;
KW Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..687
FT /note="Protein FAR1-RELATED SEQUENCE 1"
FT /id="PRO_0000363479"
FT DOMAIN 35..137
FT /note="FAR1"
FT DOMAIN 211..254
FT /note="MULE"
FT ZN_FING 440..476
FT /note="SWIM-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00325"
FT COILED 540..562
FT /evidence="ECO:0000255"
SQ SEQUENCE 687 AA; 80312 MW; 25059A7477441D64 CRC64;
MSSGECSNVQ LDDHRKNNLE IDEGREFESK EEAFEFYKEY ANSVGFTTII KASRRSRMTG
KFIDAKFVCT RYGSKKEDID TGLGTDGFNI PQARKRGRIN RSSSKTDCKA FLHVKRRQDG
RWVVRSLVKE HNHEIFTGQA DSLRELSGRR KLEKLNGAIV KEVKSRKLED GDVERLLNFF
TDMQVENPFF FYSIDLSEEQ SLRNIFWVDA KAMHGCRPRV ILTKHDQMLK EAVLEVFPSS
RHCFYMWDTL GQMPEKLGHV IRLEKKLVDE INDAIYGSCQ SEDFEKNWWE VVDRFHMRDN
VWLQSLYEDR EYWVPVYMKD VSLAGMCTAQ RSDSVNSGLD KYIQRKTTFK AFLEQYKKMI
QERYEEEEKS EIETLYKQPG LKSPSPFGKQ MAEVYTREMF KKFQVEVLGG VACHPKKESE
EDGVNKRTFR VQDYEQNRSF VVVWNSESSE VVCSCRLFEL KGFLCRHAMI VLQMSGELSI
PSQYVLKRWT KDAKSREVME SDQTDVESTK AQRYKDLCLR SLKLSEEASL SEESYNAVVN
VLNEALRKWE NKSNLIQNLE ESESVTAQDL PIHEEQNNTY DMNKDDNVAD TGQEYSLQEV
WKVTALQEQR NRYSILDDYL SAQHMSHEMG QINSMASNRN GYCSVHQNIH SLQGQSITHP
RLYETEQSSF RPEAMYERLQ DMVKDLN
