FRS3_ARATH
ID FRS3_ARATH Reviewed; 851 AA.
AC Q9ZVC9; Q2V450; Q93ZJ5;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Protein FAR1-RELATED SEQUENCE 3;
GN Name=FRS3; OrderedLocusNames=At2g27110; ORFNames=T20P8.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP TISSUE SPECIFICITY, INDUCTION, SUBCELLULAR LOCATION, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=15591448; DOI=10.1104/pp.104.052191;
RA Lin R., Wang H.;
RT "Arabidopsis FHY3/FAR1 gene family and distinct roles of its members in
RT light control of Arabidopsis development.";
RL Plant Physiol. 136:4010-4022(2004).
CC -!- FUNCTION: Putative transcription activator involved in regulating light
CC control of development.
CC -!- INTERACTION:
CC Q9ZVC9; F4JI72: At4g03250; NbExp=3; IntAct=EBI-4448729, EBI-15192535;
CC Q9ZVC9; Q9SZL8: FRS5; NbExp=5; IntAct=EBI-4448729, EBI-15194231;
CC Q9ZVC9; Q8GXL7: GATA24; NbExp=3; IntAct=EBI-4448729, EBI-4426127;
CC Q9ZVC9; Q9LRH6: GATA25; NbExp=4; IntAct=EBI-4448729, EBI-2460434;
CC Q9ZVC9; Q8H1G0: GATA28; NbExp=4; IntAct=EBI-4448729, EBI-4435064;
CC Q9ZVC9; Q84JP1: NFYA7; NbExp=3; IntAct=EBI-4448729, EBI-4444640;
CC Q9ZVC9; Q9C518: TCP8; NbExp=4; IntAct=EBI-4448729, EBI-3134124;
CC Q9ZVC9; O64647: TCP9; NbExp=5; IntAct=EBI-4448729, EBI-9838721;
CC Q9ZVC9; Q9LMA8: TIFY10A; NbExp=7; IntAct=EBI-4448729, EBI-1388539;
CC Q9ZVC9; Q9S7M2: TIFY10B; NbExp=6; IntAct=EBI-4448729, EBI-1792563;
CC Q9ZVC9; Q9LVI4: TIFY6B; NbExp=4; IntAct=EBI-4448729, EBI-1792431;
CC Q9ZVC9; Q6X7J9: WOX4; NbExp=3; IntAct=EBI-4448729, EBI-4459694;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15591448}. Note=The
CC nuclear localization is independent of the light treatment.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9ZVC9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9ZVC9-2; Sequence=VSP_036308, VSP_036309;
CC -!- TISSUE SPECIFICITY: Expressed in hypocotyls, rosette and cauline
CC leaves, inflorescences stems, flowers and siliques.
CC {ECO:0000269|PubMed:15591448}.
CC -!- INDUCTION: Up-regulated in hypocotyls by far-red light treatment.
CC {ECO:0000269|PubMed:15591448}.
CC -!- SIMILARITY: Belongs to the FHY3/FAR1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC005623; AAC77869.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC07937.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07938.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07939.1; -; Genomic_DNA.
DR EMBL; AY057491; AAL09732.1; -; mRNA.
DR EMBL; BT002690; AAO11606.1; -; mRNA.
DR PIR; H84668; H84668.
DR RefSeq; NP_001031428.1; NM_001036351.2. [Q9ZVC9-2]
DR RefSeq; NP_565636.1; NM_128269.4. [Q9ZVC9-1]
DR RefSeq; NP_850098.1; NM_179767.2. [Q9ZVC9-1]
DR AlphaFoldDB; Q9ZVC9; -.
DR SMR; Q9ZVC9; -.
DR BioGRID; 2605; 27.
DR IntAct; Q9ZVC9; 25.
DR STRING; 3702.AT2G27110.2; -.
DR PaxDb; Q9ZVC9; -.
DR PRIDE; Q9ZVC9; -.
DR ProteomicsDB; 228954; -. [Q9ZVC9-1]
DR EnsemblPlants; AT2G27110.1; AT2G27110.1; AT2G27110. [Q9ZVC9-1]
DR EnsemblPlants; AT2G27110.2; AT2G27110.2; AT2G27110. [Q9ZVC9-1]
DR EnsemblPlants; AT2G27110.3; AT2G27110.3; AT2G27110. [Q9ZVC9-2]
DR GeneID; 817253; -.
DR Gramene; AT2G27110.1; AT2G27110.1; AT2G27110. [Q9ZVC9-1]
DR Gramene; AT2G27110.2; AT2G27110.2; AT2G27110. [Q9ZVC9-1]
DR Gramene; AT2G27110.3; AT2G27110.3; AT2G27110. [Q9ZVC9-2]
DR KEGG; ath:AT2G27110; -.
DR Araport; AT2G27110; -.
DR TAIR; locus:2059304; AT2G27110.
DR eggNOG; ENOG502QSJE; Eukaryota.
DR InParanoid; Q9ZVC9; -.
DR OMA; NRMSNVF; -.
DR OrthoDB; 188741at2759; -.
DR PhylomeDB; Q9ZVC9; -.
DR PRO; PR:Q9ZVC9; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZVC9; baseline and differential.
DR Genevisible; Q9ZVC9; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR004330; FAR1_DNA_bnd_dom.
DR InterPro; IPR031052; FHY3/FAR1.
DR InterPro; IPR018289; MULE_transposase_dom.
DR InterPro; IPR006564; Znf_PMZ.
DR InterPro; IPR007527; Znf_SWIM.
DR PANTHER; PTHR31669; PTHR31669; 1.
DR Pfam; PF03101; FAR1; 1.
DR Pfam; PF10551; MULE; 1.
DR Pfam; PF04434; SWIM; 1.
DR SMART; SM00575; ZnF_PMZ; 1.
DR PROSITE; PS50966; ZF_SWIM; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Metal-binding; Nucleus; Reference proteome; Zinc;
KW Zinc-finger.
FT CHAIN 1..851
FT /note="Protein FAR1-RELATED SEQUENCE 3"
FT /id="PRO_0000363481"
FT DOMAIN 63..137
FT /note="FAR1"
FT DOMAIN 246..342
FT /note="MULE"
FT ZN_FING 525..561
FT /note="SWIM-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00325"
FT VAR_SEQ 1..145
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_036308"
FT VAR_SEQ 146..148
FT /note="PRR -> MCW (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_036309"
SQ SEQUENCE 851 AA; 96258 MW; A5149726766D9397 CRC64;
MDVHLVEENV SMGNHEIGDE GDVEPSDCSG QNNMDNSLGV QDEIGIAEPC VGMEFNSEKE
AKSFYDEYSR QLGFTSKLLP RTDGSVSVRE FVCSSSSKRS KRRLSESCDA MVRIELQGHE
KWVVTKFVKE HTHGLASSNM LHCLRPRRHF ANSEKSSYQE GVNVPSGMMY VSMDANSRGA
RNASMATNTK RTIGRDAHNL LEYFKRMQAE NPGFFYAVQL DEDNQMSNVF WADSRSRVAY
THFGDTVTLD TRYRCNQFRV PFAPFTGVNH HGQAILFGCA LILDESDTSF IWLFKTFLTA
MRDQPPVSLV TDQDRAIQIA AGQVFPGARH CINKWDVLRE GQEKLAHVCL AYPSFQVELY
NCINFTETIE EFESSWSSVI DKYDLGRHEW LNSLYNARAQ WVPVYFRDSF FAAVFPSQGY
SGSFFDGYVN QQTTLPMFFR LYERAMESWF EMEIEADLDT VNTPPVLKTP SPMENQAANL
FTRKIFGKFQ EELVETFAHT ANRIEDDGTT STFRVANFEN DNKAYIVTFC YPEMRANCSC
QMFEHSGILC RHVLTVFTVT NILTLPPHYI LRRWTRNAKS MVELDEHVSE NGHDSSIHRY
NHLCREAIKY AEEGAITAEA YNIALGQLRE GGKKVSVVRK RIGRAAPPSS HGGGIGSGDK
TSLSAADTTP LLWPRQDEMI RRFNLNDGGA RAQSVSDLNL PRMAPVSLHR DDTAPENMVA
LPCLKSLTWG MESKNTMPGG RVAVINLKLH DYRKFPSADM DVKFQLSSVT LEPMLRSMAY
ISEQLSSPAN RVAVINLKLQ DTETTTGESE VKFQVSRDTL GAMLRSMAYI REQLSIVGEL
QTESQAKKQR K
