FRS5_ARATH
ID FRS5_ARATH Reviewed; 788 AA.
AC Q9SZL8;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 105.
DE RecName: Full=Protein FAR1-RELATED SEQUENCE 5;
GN Name=FRS5; OrderedLocusNames=At4g38180; ORFNames=F20D10.300;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP TISSUE SPECIFICITY, INDUCTION, SUBCELLULAR LOCATION, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=15591448; DOI=10.1104/pp.104.052191;
RA Lin R., Wang H.;
RT "Arabidopsis FHY3/FAR1 gene family and distinct roles of its members in
RT light control of Arabidopsis development.";
RL Plant Physiol. 136:4010-4022(2004).
CC -!- FUNCTION: Putative transcription activator involved in regulating light
CC control of development.
CC -!- INTERACTION:
CC Q9SZL8; Q9LV59: At3g24490; NbExp=3; IntAct=EBI-15194231, EBI-15191981;
CC Q9SZL8; Q93Z68: At3g59470; NbExp=4; IntAct=EBI-15194231, EBI-4432826;
CC Q9SZL8; F4JI72: At4g03250; NbExp=3; IntAct=EBI-15194231, EBI-15192535;
CC Q9SZL8; Q9ZVC9: FRS3; NbExp=5; IntAct=EBI-15194231, EBI-4448729;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15591448}. Note=The
CC nuclear localization is independent of the light treatment.
CC -!- TISSUE SPECIFICITY: Expressed in hypocotyls, rosette and cauline
CC leaves, inflorescences stems, flowers and siliques.
CC {ECO:0000269|PubMed:15591448}.
CC -!- INDUCTION: Up-regulated in hypocotyls by far-red light treatment.
CC {ECO:0000269|PubMed:15591448}.
CC -!- SIMILARITY: Belongs to the FHY3/FAR1 family. {ECO:0000305}.
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DR EMBL; AL035538; CAB37558.1; -; Genomic_DNA.
DR EMBL; AL161593; CAB80483.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE86890.1; -; Genomic_DNA.
DR EMBL; AY136457; AAM97122.1; -; mRNA.
DR PIR; T05645; T05645.
DR RefSeq; NP_195531.1; NM_119979.3.
DR AlphaFoldDB; Q9SZL8; -.
DR BioGRID; 15254; 18.
DR IntAct; Q9SZL8; 18.
DR STRING; 3702.AT4G38180.1; -.
DR PaxDb; Q9SZL8; -.
DR PRIDE; Q9SZL8; -.
DR ProteomicsDB; 230000; -.
DR EnsemblPlants; AT4G38180.1; AT4G38180.1; AT4G38180.
DR GeneID; 829974; -.
DR Gramene; AT4G38180.1; AT4G38180.1; AT4G38180.
DR KEGG; ath:AT4G38180; -.
DR Araport; AT4G38180; -.
DR TAIR; locus:2121060; AT4G38180.
DR eggNOG; ENOG502QR4C; Eukaryota.
DR HOGENOM; CLU_008459_7_3_1; -.
DR InParanoid; Q9SZL8; -.
DR OMA; ELRDHEW; -.
DR OrthoDB; 165059at2759; -.
DR PhylomeDB; Q9SZL8; -.
DR PRO; PR:Q9SZL8; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9SZL8; baseline and differential.
DR Genevisible; Q9SZL8; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR004330; FAR1_DNA_bnd_dom.
DR InterPro; IPR031052; FHY3/FAR1.
DR InterPro; IPR018289; MULE_transposase_dom.
DR InterPro; IPR006564; Znf_PMZ.
DR InterPro; IPR007527; Znf_SWIM.
DR PANTHER; PTHR31669; PTHR31669; 1.
DR Pfam; PF03101; FAR1; 1.
DR Pfam; PF10551; MULE; 1.
DR Pfam; PF04434; SWIM; 1.
DR SMART; SM00575; ZnF_PMZ; 1.
DR PROSITE; PS50966; ZF_SWIM; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..788
FT /note="Protein FAR1-RELATED SEQUENCE 5"
FT /id="PRO_0000363483"
FT DOMAIN 87..179
FT /note="FAR1"
FT DOMAIN 299..395
FT /note="MULE"
FT ZN_FING 584..616
FT /note="SWIM-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00325"
FT REGION 713..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 731..768
FT /evidence="ECO:0000255"
SQ SEQUENCE 788 AA; 90485 MW; 46471B2214F16506 CRC64;
MMDNEVLDFD IGVGVSSGGD VDDDAIDIEH HALDDDDMLD SPIMPCGNGL VGNSGNYFPN
QEEEACDLLD LEPYDGLEFE SEEAAKAFYN SYARRIGFST RVSSSRRSRR DGAIIQRQFV
CAKEGFRNMN EKRTKDREIK RPRTITRVGC KASLSVKMQD SGKWLVSGFV KDHNHELVPP
DQVHCLRSHR QISGPAKTLI DTLQAAGMGP RRIMSALIKE YGGISKVGFT EVDCRNYMRN
NRQKSIEGEI QLLLDYLRQM NADNPNFFYS VQGSEDQSVG NVFWADPKAI MDFTHFGDTV
TFDTTYRSNR YRLPFAPFTG VNHHGQPILF GCAFIINETE ASFVWLFNTW LAAMSAHPPV
SITTDHDAVI RAAIMHVFPG ARHRFCKWHI LKKCQEKLSH VFLKHPSFES DFHKCVNLTE
SVEDFERCWF SLLDKYELRD HEWLQAIYSD RRQWVPVYLR DTFFADMSLT HRSDSINSYF
DGYINASTNL SQFFKLYEKA LESRLEKEVK ADYDTMNSPP VLKTPSPMEK QASELYTRKL
FMRFQEELVG TLTFMASKAD DDGDLVTYQV AKYGEAHKAH FVKFNVLEMR ANCSCQMFEF
SGIICRHILA VFRVTNLLTL PPYYILKRWT RNAKSSVIFD DYNLHAYANY LESHTVRYNT
LRHKASNFVQ EAGKSLYTCD VAVVALQEAA KTVSLAMNKE VRRTMANRHF KASSVTGGKH
QQEVLAQPEP EDEMDKKINQ LRNELELANR KCEAYRTNLL SVLKEMEDQK LQVSIKVQNI
KISLKDNL
