FRS6_ARATH
ID FRS6_ARATH Reviewed; 703 AA.
AC Q9SSQ4;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Protein FAR1-RELATED SEQUENCE 6;
GN Name=FRS6; OrderedLocusNames=At1g52520; ORFNames=F6D8.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, TISSUE SPECIFICITY, INDUCTION, SUBCELLULAR LOCATION, GENE FAMILY,
RP AND NOMENCLATURE.
RX PubMed=15591448; DOI=10.1104/pp.104.052191;
RA Lin R., Wang H.;
RT "Arabidopsis FHY3/FAR1 gene family and distinct roles of its members in
RT light control of Arabidopsis development.";
RL Plant Physiol. 136:4010-4022(2004).
CC -!- FUNCTION: Putative transcription activator involved in regulating light
CC control of development. May have a role in controlling flowering time.
CC {ECO:0000269|PubMed:15591448}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15591448}. Note=The
CC nuclear localization is independent of the light treatment.
CC -!- TISSUE SPECIFICITY: Expressed in hypocotyls, rosette and cauline
CC leaves, inflorescences stems, flowers and siliques.
CC {ECO:0000269|PubMed:15591448}.
CC -!- INDUCTION: Up-regulated in hypocotyls by far-red light treatment.
CC {ECO:0000269|PubMed:15591448}.
CC -!- SIMILARITY: Belongs to the FHY3/FAR1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC008016; AAD55625.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32818.1; -; Genomic_DNA.
DR EMBL; AY080775; AAL87259.1; -; mRNA.
DR EMBL; AY133776; AAM91710.1; -; mRNA.
DR PIR; G96565; G96565.
DR RefSeq; NP_175661.1; NM_104130.4.
DR AlphaFoldDB; Q9SSQ4; -.
DR STRING; 3702.AT1G52520.1; -.
DR PaxDb; Q9SSQ4; -.
DR PRIDE; Q9SSQ4; -.
DR ProteomicsDB; 228955; -.
DR EnsemblPlants; AT1G52520.1; AT1G52520.1; AT1G52520.
DR GeneID; 841683; -.
DR Gramene; AT1G52520.1; AT1G52520.1; AT1G52520.
DR KEGG; ath:AT1G52520; -.
DR Araport; AT1G52520; -.
DR TAIR; locus:2035144; AT1G52520.
DR eggNOG; ENOG502QS51; Eukaryota.
DR HOGENOM; CLU_008459_7_0_1; -.
DR InParanoid; Q9SSQ4; -.
DR OMA; EDRFRWA; -.
DR OrthoDB; 259883at2759; -.
DR PhylomeDB; Q9SSQ4; -.
DR PRO; PR:Q9SSQ4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SSQ4; baseline and differential.
DR Genevisible; Q9SSQ4; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR004330; FAR1_DNA_bnd_dom.
DR InterPro; IPR031052; FHY3/FAR1.
DR InterPro; IPR018289; MULE_transposase_dom.
DR InterPro; IPR006564; Znf_PMZ.
DR InterPro; IPR007527; Znf_SWIM.
DR PANTHER; PTHR31669; PTHR31669; 1.
DR Pfam; PF03101; FAR1; 1.
DR Pfam; PF10551; MULE; 1.
DR Pfam; PF04434; SWIM; 1.
DR SMART; SM00575; ZnF_PMZ; 1.
DR PROSITE; PS50966; ZF_SWIM; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..703
FT /note="Protein FAR1-RELATED SEQUENCE 6"
FT /id="PRO_0000363484"
FT DOMAIN 99..184
FT /note="FAR1"
FT DOMAIN 297..392
FT /note="MULE"
FT ZN_FING 584..620
FT /note="SWIM-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00325"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 703 AA; 81604 MW; 55220EE17C59EC46 CRC64;
MERSESVDED VQASAYLEND EVRERDDPMS DTLRIGEEAL VCSSEHEIDV GFCQNEERKS
EEETMGGFDE QSGLLVDERK EFDAPAVGME FESYDDAYNY YNCYASEVGF RVRVKNSWFK
RRSKEKYGAV LCCSSQGFKR INDVNRVRKE TRTGCPAMIR MRQVDSKRWR VVEVTLDHNH
LLGCKLYKSV KRKRKCVSSP VSDAKTIKLY RACVVDNGSN VNPNSTLNKK FQNSTGSPDL
LNLKRGDSAA IYNYFCRMQL TNPNFFYLMD VNDEGQLRNV FWADAFSKVS CSYFGDVIFI
DSSYISGKFE IPLVTFTGVN HHGKTTLLSC GFLAGETMES YHWLLKVWLS VMKRSPQTIV
TDRCKPLEAA ISQVFPRSHQ RFSLTHIMRK IPEKLGGLHN YDAVRKAFTK AVYETLKVVE
FEAAWGFMVH NFGVIENEWL RSLYEERAKW APVYLKDTFF AGIAAAHPGE TLKPFFERYV
HKQTPLKEFL DKYELALQKK HREETLSDIE SQTLNTAELK TKCSFETQLS RIYTRDMFKK
FQIEVEEMYS CFSTTQVHVD GPFVIFLVKE RVRGESSRRE IRDFEVLYNR SVGEVRCICS
CFNFYGYLCR HALCVLNFNG VEEIPLRYIL PRWRKDYKRL HFADNGLTGF VDGTDRVQWF
DQLYKNSLQV VEEGAVSLDH YKVAMQVLQE SLDKVHSVEE KQD
