ID   FRSA_CITK8              Reviewed;         414 AA.
AC   A8AKP9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Esterase FrsA {ECO:0000255|HAMAP-Rule:MF_01063};
DE            EC=3.1.1.1 {ECO:0000255|HAMAP-Rule:MF_01063};
GN   Name=frsA {ECO:0000255|HAMAP-Rule:MF_01063}; OrderedLocusNames=CKO_02957;
OS   Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Citrobacter.
OX   NCBI_TaxID=290338;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696;
RG   The Citrobacter koseri Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA   Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA   Johnson M., Thiruvilangam P., Wilson R.;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC         Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01063};
CC   -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
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DR   EMBL; CP000822; ABV14062.1; -; Genomic_DNA.
DR   RefSeq; WP_012133775.1; NC_009792.1.
DR   AlphaFoldDB; A8AKP9; -.
DR   SMR; A8AKP9; -.
DR   STRING; 290338.CKO_02957; -.
DR   ESTHER; citk8-y2957; Duf_1100-R.
DR   EnsemblBacteria; ABV14062; ABV14062; CKO_02957.
DR   GeneID; 45136773; -.
DR   KEGG; cko:CKO_02957; -.
DR   HOGENOM; CLU_036819_0_0_6; -.
DR   OMA; NIPWVDH; -.
DR   OrthoDB; 721431at2; -.
DR   Proteomes; UP000008148; Chromosome.
DR   GO; GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   HAMAP; MF_01063; FrsA; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR043423; FrsA.
DR   InterPro; IPR010520; FrsA-like.
DR   Pfam; PF06500; FrsA-like; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome; Serine esterase.
FT   CHAIN           1..414
FT                   /note="Esterase FrsA"
FT                   /id="PRO_1000064476"
SQ   SEQUENCE   414 AA;  46946 MW;  68AACC57AD329513 CRC64;
     MSQANLSETL FKPRFKHPET STLVRRFNHG TQPSVQSTLD GKNVPHWYRM INRLMWIWRG
     IDPREILDVQ ARIVMSEAER TDKELYDTVI GYRGGNWIFE WSKQAMEWQQ KACQETDPQR
     SGRHWLHASS LYNIAAYPHL KGDELAEQAQ ALANRAYEEA AQRLPGSLRE MAFSIPGGAP
     VTAFLHMPKG DGPFPTVLMC GGLDSMQTDY YTLFERYFAP RGMAMLTLDM PSVGFSSKWK
     LTQDSSLLHQ HVLKALPGVP WVDHTRVVAF GFRFGANVAV RLAYLEAPRL KAVACLGPVV
     HALLSDSQRQ GTVPEMYLDV LASRLGMHDA SDEALRVELN RYSLKVQGLL GRRCPTPMLS
     GFWKNDPFSP EEESRLITSS SSDGKLMEIP FNPVYRNFDT ALKEITGWIN HRLC