ID   FRSA_ENT38              Reviewed;         414 AA.
AC   A4W6X1;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Esterase FrsA {ECO:0000255|HAMAP-Rule:MF_01063};
DE            EC=3.1.1.1 {ECO:0000255|HAMAP-Rule:MF_01063};
GN   Name=frsA {ECO:0000255|HAMAP-Rule:MF_01063}; OrderedLocusNames=Ent638_0765;
OS   Enterobacter sp. (strain 638).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=399742;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=638;
RX   PubMed=20485560; DOI=10.1371/journal.pgen.1000943;
RA   Taghavi S., van der Lelie D., Hoffman A., Zhang Y.B., Walla M.D.,
RA   Vangronsveld J., Newman L., Monchy S.;
RT   "Genome sequence of the plant growth promoting endophytic bacterium
RT   Enterobacter sp. 638.";
RL   PLoS Genet. 6:E1000943-E1000943(2010).
CC   -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC         Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01063};
CC   -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
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DR   EMBL; CP000653; ABP59451.1; -; Genomic_DNA.
DR   RefSeq; WP_012016172.1; NC_009436.1.
DR   AlphaFoldDB; A4W6X1; -.
DR   SMR; A4W6X1; -.
DR   STRING; 399742.Ent638_0765; -.
DR   ESTHER; ent38-y765; Duf_1100-R.
DR   EnsemblBacteria; ABP59451; ABP59451; Ent638_0765.
DR   KEGG; ent:Ent638_0765; -.
DR   eggNOG; COG1073; Bacteria.
DR   HOGENOM; CLU_036819_0_0_6; -.
DR   OMA; NIPWVDH; -.
DR   OrthoDB; 721431at2; -.
DR   Proteomes; UP000000230; Chromosome.
DR   GO; GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   HAMAP; MF_01063; FrsA; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR043423; FrsA.
DR   InterPro; IPR010520; FrsA-like.
DR   Pfam; PF06500; FrsA-like; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Serine esterase.
FT   CHAIN           1..414
FT                   /note="Esterase FrsA"
FT                   /id="PRO_1000064482"
SQ   SEQUENCE   414 AA;  46824 MW;  C68731E6A0182240 CRC64;
     MTQANLSETL FKPRFKHPET STLVRRFNPG TQPAVQSTLD GKTVPHWYRM INRLMWIWRG
     IDAREILEVQ ARIVMSEADR TDSELYDTVV GYRGGNWIYE WATQAMVWQQ KATQEPDQTL
     SGQHWLHAAN LYSIAAYPHL KGDDLAEQAQ ALANRAYEEA AQRLPCNMRE IEFPIPGGAS
     VTGFLHMPPG EGPFPTVLMC GGLDSLQIDY YSLFERYFAP KGIAMLTLDM PSIGFSSKWK
     LTQDSSLLHQ HALKALENIP WVDHTRVAAF GFRFGANVAV RLAYLESSRL KAVACLGPVV
     HALLSDPQRQ ASVPEMYLDV LASRLGMHDA SDEALRVELN RYSLKTQGLL GRRCPTPMMS
     GFWKNDPFSP EEESRLITSS SLDGKLLEIP FSPVYQNFDK GLKEITRWIT QRLC