ID   FRSA_ERWT9              Reviewed;         416 AA.
AC   B2VHN2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Esterase FrsA {ECO:0000255|HAMAP-Rule:MF_01063};
DE            EC=3.1.1.1 {ECO:0000255|HAMAP-Rule:MF_01063};
GN   Name=frsA {ECO:0000255|HAMAP-Rule:MF_01063}; OrderedLocusNames=ETA_25970;
OS   Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB
OS   4357 / Et1/99).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Erwinia.
OX   NCBI_TaxID=465817;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99;
RX   PubMed=18462403; DOI=10.1111/j.1462-2920.2008.01639.x;
RA   Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R.,
RA   Geider K.;
RT   "The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic
RT   bacterium in the genus Erwinia.";
RL   Environ. Microbiol. 10:2211-2222(2008).
CC   -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC         Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01063};
CC   -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
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DR   EMBL; CU468135; CAO97643.1; -; Genomic_DNA.
DR   RefSeq; WP_012442308.1; NC_010694.1.
DR   AlphaFoldDB; B2VHN2; -.
DR   SMR; B2VHN2; -.
DR   STRING; 465817.ETA_25970; -.
DR   ESTHER; erwt9-y2597; Duf_1100-R.
DR   EnsemblBacteria; CAO97643; CAO97643; ETA_25970.
DR   KEGG; eta:ETA_25970; -.
DR   eggNOG; COG1073; Bacteria.
DR   HOGENOM; CLU_036819_0_0_6; -.
DR   OMA; NIPWVDH; -.
DR   OrthoDB; 721431at2; -.
DR   Proteomes; UP000001726; Chromosome.
DR   GO; GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   HAMAP; MF_01063; FrsA; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR043423; FrsA.
DR   InterPro; IPR010520; FrsA-like.
DR   Pfam; PF06500; FrsA-like; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome; Serine esterase.
FT   CHAIN           1..416
FT                   /note="Esterase FrsA"
FT                   /id="PRO_1000136517"
SQ   SEQUENCE   416 AA;  46766 MW;  220875B414679FB7 CRC64;
     MPPKNLSEEL FKPRFKHPET SSLVRRVRHH HPFLIHAALG GEHSVGWYRT IDRLLWAWRG
     LSPQEIVEVL SRIAASTSEH TDERLLDTVM GYRGGNWIYE WSKQGALWQQ KASQNHDEQQ
     AGHCWLQAAN LYSVASYPHL KEDPLAEQAQ LLASRAYQQA TLLLPGELKE LEFAIPGGSP
     VSGFLHMPPD ARPPYPTVLM CGSLDSLQSD HYRLFHDYLA PRGIALLTLD MPSVGFSAKW
     KLTQDTSFLH QQVLRQLENV AWVDHTRVAA FGYRFGANIA VRLASLETHR LRAVACLGPV
     VHRLLTDTDL QDRVPDMYMD MLASRLGMSG TSDGTLRTEL SCFSLKMQGL LGRRLPTPML
     SACWANDPFS PEEESRLIVN SSSAGRLLKI PTSPARIGFD TALRDMSDWL LAKLTL