ID   FRSA_PHOLL              Reviewed;         415 AA.
AC   Q7N7B3;
DT   15-DEC-2003, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Esterase FrsA {ECO:0000255|HAMAP-Rule:MF_01063};
DE            EC=3.1.1.1 {ECO:0000255|HAMAP-Rule:MF_01063};
GN   Name=frsA {ECO:0000255|HAMAP-Rule:MF_01063}; OrderedLocusNames=plu1242;
OS   Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS   TT01).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Photorhabdus.
OX   NCBI_TaxID=243265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15139 / CIP 105565 / TT01;
RX   PubMed=14528314; DOI=10.1038/nbt886;
RA   Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA   Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA   Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA   Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA   Glaser P., Boemare N., Danchin A., Kunst F.;
RT   "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT   luminescens.";
RL   Nat. Biotechnol. 21:1307-1313(2003).
CC   -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC         Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01063};
CC   -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BX571863; CAE13536.1; -; Genomic_DNA.
DR   RefSeq; WP_011145567.1; NC_005126.1.
DR   AlphaFoldDB; Q7N7B3; -.
DR   SMR; Q7N7B3; -.
DR   STRING; 243265.plu1242; -.
DR   ESTHER; pholl-y1242; Duf_1100-R.
DR   PRIDE; Q7N7B3; -.
DR   EnsemblBacteria; CAE13536; CAE13536; plu1242.
DR   GeneID; 24167417; -.
DR   KEGG; plu:plu1242; -.
DR   eggNOG; COG1073; Bacteria.
DR   HOGENOM; CLU_036819_0_0_6; -.
DR   OMA; NIPWVDH; -.
DR   OrthoDB; 721431at2; -.
DR   BioCyc; PLUM243265:PLU_RS06135-MON; -.
DR   Proteomes; UP000002514; Chromosome.
DR   GO; GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   HAMAP; MF_01063; FrsA; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR043423; FrsA.
DR   InterPro; IPR010520; FrsA-like.
DR   Pfam; PF06500; FrsA-like; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome; Serine esterase.
FT   CHAIN           1..415
FT                   /note="Esterase FrsA"
FT                   /id="PRO_0000197154"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   415 AA;  47772 MW;  38D2C09DFBC5EFDF CRC64;
     MANRNLSESL FKPRQKHQET STLVKHRDPR LIAGNYSTLD GNSHGSWYRM INRLMWIWRE
     IDPFEIEEVL CRIAMTNAQR SDDNLLDTVI GYRKGNWVFE WSHQAMLWQQ RALQAEQIPE
     ASNFWLKAAN LYSIAGYPHL KGDELSQQAV ILANKAYENA ARCSGYQLRK IEFKLKEGGC
     VTGFLHLPQQ LQRPSPTILV CGSLDNLQSD YYRLFRDYLA PLGFAMLTVD MPSIGYSSRL
     RMTQDTCILH QQIIHQLDEI PWIDHTRIGL FGFRFGANIA VRLAYLESKR IKGVATLGAI
     VHEWLSSVER QQNSPSMYLD MFASRLGIYN VDEKAFRLEL GCYSLKKQGL LGRRCSVPML
     AGYWQNDIFS PKEESKLIAM SSMDSQLLAI PTTPVYNSFN KALREISQWL RNKVC