ID   FRSA_PHOPR              Reviewed;         419 AA.
AC   Q6LTX5;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Esterase FrsA {ECO:0000255|HAMAP-Rule:MF_01063};
DE            EC=3.1.1.1 {ECO:0000255|HAMAP-Rule:MF_01063};
GN   Name=frsA {ECO:0000255|HAMAP-Rule:MF_01063}; OrderedLocusNames=PBPRA0837;
OS   Photobacterium profundum (strain SS9).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=298386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1253 / SS9;
RX   PubMed=15746425; DOI=10.1126/science.1103341;
RA   Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA   Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA   Bartlett D.H., Valle G.;
RT   "Life at depth: Photobacterium profundum genome sequence and expression
RT   analysis.";
RL   Science 307:1459-1461(2005).
CC   -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC         Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01063};
CC   -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR378665; CAG19250.1; -; Genomic_DNA.
DR   RefSeq; WP_011217587.1; NC_006370.1.
DR   AlphaFoldDB; Q6LTX5; -.
DR   SMR; Q6LTX5; -.
DR   STRING; 298386.PBPRA0837; -.
DR   ESTHER; phopr-y837; Duf_1100-R.
DR   PRIDE; Q6LTX5; -.
DR   EnsemblBacteria; CAG19250; CAG19250; PBPRA0837.
DR   KEGG; ppr:PBPRA0837; -.
DR   eggNOG; COG1073; Bacteria.
DR   HOGENOM; CLU_036819_0_0_6; -.
DR   OMA; NIPWVDH; -.
DR   OrthoDB; 721431at2; -.
DR   Proteomes; UP000000593; Chromosome 1.
DR   GO; GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   HAMAP; MF_01063; FrsA; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR043423; FrsA.
DR   InterPro; IPR010520; FrsA-like.
DR   Pfam; PF06500; FrsA-like; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome; Serine esterase.
FT   CHAIN           1..419
FT                   /note="Esterase FrsA"
FT                   /id="PRO_0000197155"
SQ   SEQUENCE   419 AA;  46776 MW;  A4D100D9E45B633D CRC64;
     MSDTSKTNLS EQLFAPRMNT KETSNLVKIA NLKSASVHNA LDGDSESGWY RVLRRPQWIW
     QGIDPIEMEA ILSRMASSTA TRTSDELLDT VIGYKPGNWI YEWTQVGAKL QKKARAYVEA
     GQKEKAADTL LKASMYYSVA AYPHLKGDTL AAQAEIQANQ SYRESMALTP HQIRTIDVKY
     EGKTFQAFIH LPRTDKLLPT VIVSGGLDSL QSDLWRLYRD YFGPAGFAMV TLDMPSVGHS
     SRWALTEDTS RLHQALVQQI RDVPWVDNTK VAMLGLRFGA NAAIRLGFME PTRLKTCISL
     GGAIHSMLTQ PTMLDSMPRM YLDVIASRMG KHGVSKSSLT SHLPAWSLKN QGLLGRRKVD
     VPMLGISLKN DPVCREIDNQ LIEKSSRGGK AITLPDTPLH DGYHRSMVTV IEWLKDKLA