ID   FRSA_SERP5              Reviewed;         415 AA.
AC   A8GAD1;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Esterase FrsA {ECO:0000255|HAMAP-Rule:MF_01063};
DE            EC=3.1.1.1 {ECO:0000255|HAMAP-Rule:MF_01063};
GN   Name=frsA {ECO:0000255|HAMAP-Rule:MF_01063}; OrderedLocusNames=Spro_0965;
OS   Serratia proteamaculans (strain 568).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=399741;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=568;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA   Vangronsveld J., van der Lelie D., Richardson P.;
RT   "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC         Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01063};
CC   -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
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DR   EMBL; CP000826; ABV40071.1; -; Genomic_DNA.
DR   RefSeq; WP_012005408.1; NC_009832.1.
DR   AlphaFoldDB; A8GAD1; -.
DR   SMR; A8GAD1; -.
DR   STRING; 399741.Spro_0965; -.
DR   ESTHER; serp5-y965; Duf_1100-R.
DR   EnsemblBacteria; ABV40071; ABV40071; Spro_0965.
DR   KEGG; spe:Spro_0965; -.
DR   eggNOG; COG1073; Bacteria.
DR   HOGENOM; CLU_036819_0_0_6; -.
DR   OMA; NIPWVDH; -.
DR   OrthoDB; 721431at2; -.
DR   GO; GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   HAMAP; MF_01063; FrsA; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR043423; FrsA.
DR   InterPro; IPR010520; FrsA-like.
DR   Pfam; PF06500; FrsA-like; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Serine esterase.
FT   CHAIN           1..415
FT                   /note="Esterase FrsA"
FT                   /id="PRO_1000064487"
SQ   SEQUENCE   415 AA;  47130 MW;  13A813BBE432A1E1 CRC64;
     MAQANLSEIL FKPSFKHPET STLVLRARSK ISAELHSTLE GNTVSNWYRM LNPLLWAWRG
     VDPIEINEVL ARIAVADVEH TNDKWLDTVV GYRNGNWIYE WVHQGMLWQQ RALEQQDPLT
     GGQYWLNAAN FYSIAGYPHL KGDELAEQAE ALSNRAYEEA ALLLPYQLKE LEFRIEGGSS
     ITGFLHLPEK GEAPFPTVLM CGSLDTLQTD YHRLFRDYLA PHGIAMLTID MPSIGSSYKW
     KLTQDSSFLH QQVLTQLTTV PWIDHQRVTA FGFRFGANVA VRLAYLEPQR LRGVACLGPV
     VHRLLCDSST QKHVPDMYMD VLASRMGMAN ASDHVLKVEL NSYSLKTQGL LGRRCPTPML
     AGYWEQDPLS PKEESQLIVS SSMDGKLIAI PRKPVYSSFH KALLQMSHWM KDKMR