ID   FRSA_VIBVY              Reviewed;         415 AA.
AC   Q7MN61;
DT   15-DEC-2003, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Esterase FrsA {ECO:0000255|HAMAP-Rule:MF_01063};
DE            EC=3.1.1.1 {ECO:0000255|HAMAP-Rule:MF_01063};
GN   Name=frsA {ECO:0000255|HAMAP-Rule:MF_01063}; OrderedLocusNames=VV0856;
OS   Vibrio vulnificus (strain YJ016).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=196600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJ016;
RX   PubMed=14656965; DOI=10.1101/gr.1295503;
RA   Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L.,
RA   Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P.,
RA   Lee C.-T., Hor L.-I., Tsai S.-F.;
RT   "Comparative genome analysis of Vibrio vulnificus, a marine pathogen.";
RL   Genome Res. 13:2577-2587(2003).
CC   -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC         Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01063};
CC   -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC93620.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000037; BAC93620.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_011078432.1; NC_005139.1.
DR   AlphaFoldDB; Q7MN61; -.
DR   SMR; Q7MN61; -.
DR   STRING; 672.VV93_v1c07950; -.
DR   ESTHER; vibvy-y856; Duf_1100-R.
DR   EnsemblBacteria; BAC93620; BAC93620; BAC93620.
DR   KEGG; vvy:VV0856; -.
DR   eggNOG; COG1073; Bacteria.
DR   HOGENOM; CLU_036819_0_0_6; -.
DR   OMA; NIPWVDH; -.
DR   OrthoDB; 721431at2; -.
DR   Proteomes; UP000002675; Chromosome I.
DR   GO; GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   HAMAP; MF_01063; FrsA; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR043423; FrsA.
DR   InterPro; IPR010520; FrsA-like.
DR   Pfam; PF06500; FrsA-like; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome; Serine esterase.
FT   CHAIN           1..415
FT                   /note="Esterase FrsA"
FT                   /id="PRO_0000197162"
SQ   SEQUENCE   415 AA;  47013 MW;  DD57542CB1483B38 CRC64;
     MSEEVSKNLS ETLFVKHKQA KETSALTQYM PTSQSLLDEI KEKNGFSWYR NLRRLQWVWQ
     GVDPIEQEQV LARIASSKHS RTDEQWLDTV MGYHSGNWAY EWTRLGMEHQ KRAGEMTNEA
     ASEALFSASL CYSIAGYPHL KSDNLAIQAQ VLANSAYLEA AKKSKYIIKQ LEIPFEKGKI
     TAHLHLTNTD KPHPVVIVSA GLDSLQTDMW RLFRDHLAKH DIAMLTVDMP SVGYSSKYPL
     TEDYSRLHQA VLNELFSIPY VDHHRVGLIG FRFGGNAMVR LSFLEQEKIK ACVILGAPIH
     DIFASPQKLQ QMPKMYLDVL ASRLGKSVVD IYSLSGQMAA WSLKVQGFLS SRKTKVPILA
     MSLEGDPVSP YSDNQMVAFF STYGKAKKIS SKTITQGYEQ SLDLAIKWLE DELLR