ID   FRSA_YERE8              Reviewed;         415 AA.
AC   A1JNX9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Esterase FrsA {ECO:0000255|HAMAP-Rule:MF_01063};
DE            EC=3.1.1.1 {ECO:0000255|HAMAP-Rule:MF_01063};
GN   Name=frsA {ECO:0000255|HAMAP-Rule:MF_01063}; OrderedLocusNames=YE3204;
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS   8081).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=393305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13174 / 8081;
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the high
RT   pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC         Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01063};
CC   -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
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DR   EMBL; AM286415; CAL13236.1; -; Genomic_DNA.
DR   RefSeq; WP_011816927.1; NC_008800.1.
DR   RefSeq; YP_001007380.1; NC_008800.1.
DR   AlphaFoldDB; A1JNX9; -.
DR   SMR; A1JNX9; -.
DR   STRING; 393305.YE3204; -.
DR   ESTHER; yere8-y3204; Duf_1100-R.
DR   EnsemblBacteria; CAL13236; CAL13236; YE3204.
DR   KEGG; yen:YE3204; -.
DR   PATRIC; fig|393305.7.peg.3407; -.
DR   eggNOG; COG1073; Bacteria.
DR   HOGENOM; CLU_036819_0_0_6; -.
DR   OMA; NIPWVDH; -.
DR   BioCyc; YENT393305:G13HL-3105-MON; -.
DR   Proteomes; UP000000642; Chromosome.
DR   GO; GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   HAMAP; MF_01063; FrsA; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR043423; FrsA.
DR   InterPro; IPR010520; FrsA-like.
DR   Pfam; PF06500; FrsA-like; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Serine esterase.
FT   CHAIN           1..415
FT                   /note="Esterase FrsA"
FT                   /id="PRO_1000064492"
SQ   SEQUENCE   415 AA;  46921 MW;  1FD339FB0730CB4F CRC64;
     MAQANLSEIL FKPKFKHPET STLVRHAHCN QAMNVHSALD GDTTSHWYRM INRLIWTWRG
     VDPLEIEEVL SRIACSKAEH SDNELLDTVV GYRNGNWIYE WAHQGMQWQQ KAMEEADPMN
     AGQYWLNAAN LYSIAGYPHL KGDELAEQVE VLSNRAYEEA AKHLPYTLKE LSFDISDGGT
     LTGFLHMPTI GSAPFPTVLM CGGLDTLQSD YHRLFRDYLA PKGIAMLTID LPSVGASSKW
     KLTQDTSFLH QQVLQALPNI PWIDHLRVSV FGFRFGANVA VRLGYLEPQR VRAVACLGPI
     VHHLLCNADS QRKLPDMYMD VMASRLGMAD AADEILRAEM NRYSLKTQGL LGRRCQTPML
     AGFWENDPFS PKEEAKLICS SSADGKLLPI SSTPLYDNFH RALLQTSQWL EDKMR