ID   FRZA_MYXXA              Reviewed;         160 AA.
AC   P43498;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Protein FrzA;
DE   AltName: Full=Frizzy aggregation protein A;
GN   Name=frzA;
OS   Myxococcus xanthus.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=34;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2492105; DOI=10.1073/pnas.86.2.424;
RA   McBride M.J., Weinberg R.A., Zusman D.R.;
RT   "'Frizzy' aggregation genes of the gliding bacterium Myxococcus xanthus
RT   show sequence similarities to the chemotaxis genes of enteric bacteria.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:424-428(1989).
CC   -!- FUNCTION: Necessary for proper aggregation of cells to form fruiting
CC       bodies. FRZ genes define a system of signal transduction analogous to
CC       the enterobacterial chemotaxis systems.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; J04157; AAA25393.1; -; Genomic_DNA.
DR   PIR; A32185; A32185.
DR   RefSeq; WP_011554146.1; NZ_JABFNT010000152.1.
DR   AlphaFoldDB; P43498; -.
DR   SMR; P43498; -.
DR   GeneID; 41361462; -.
DR   OMA; PEQEFFC; -.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR039315; CheW.
DR   InterPro; IPR036061; CheW-like_dom_sf.
DR   InterPro; IPR002545; CheW-lke_dom.
DR   PANTHER; PTHR22617; PTHR22617; 1.
DR   Pfam; PF01584; CheW; 1.
DR   SMART; SM00260; CheW; 1.
DR   SUPFAM; SSF50341; SSF50341; 1.
DR   PROSITE; PS50851; CHEW; 1.
PE   4: Predicted;
KW   Chemotaxis; Transducer.
FT   CHAIN           1..160
FT                   /note="Protein FrzA"
FT                   /id="PRO_0000198351"
FT   DOMAIN          14..155
FT                   /note="CheW-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00052"
SQ   SEQUENCE   160 AA;  17110 MW;  26ED29B05B545A64 CRC64;
     MAPDRALAAQ ARPEQEFFCF RVGDLRLGVP SENVLEVLRA GLLTPLPRTP SFIMGVTGHR
     GEVLPVLDLL RFLSKGEARI GPRTRLFVGV TGSYVAGVVA DTVLGLRRIP VADILPPPLG
     GDAAAEHLLG VVQASGNQEA INLLNFSKLL QTARQRAVAR