ID   FSA6_FUSSF              Reviewed;         751 AA.
AC   A0A0E4AZF8;
DT   30-AUG-2017, integrated into UniProtKB/Swiss-Prot.
DT   24-JUN-2015, sequence version 1.
DT   25-MAY-2022, entry version 21.
DE   RecName: Full=Fusarisetin A cluster transcription factor fsa6 {ECO:0000303|PubMed:25770422};
DE   AltName: Full=Fusarisetin A biosynthesis protein 6 {ECO:0000303|PubMed:25770422};
GN   Name=fsa6 {ECO:0000303|PubMed:25770422};
OS   Fusarium sp. (strain FN080326).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX   NCBI_TaxID=1608308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND DISRUPTION PHENOTYPE.
RX   PubMed=25770422; DOI=10.1016/j.bbrc.2015.03.011;
RA   Kato N., Nogawa T., Hirota H., Jang J.H., Takahashi S., Ahn J.S., Osada H.;
RT   "A new enzyme involved in the control of the stereochemistry in the decalin
RT   formation during equisetin biosynthesis.";
RL   Biochem. Biophys. Res. Commun. 460:210-215(2015).
CC   -!- FUNCTION: Transcription factor that regulates the expression of the
CC       gene cluster that mediates the biosynthesis of fusarisetin A
CC       (PubMed:25770422). {ECO:0000305|PubMed:25770422}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Fairly reduces the production of fusarisetin A
CC       (PubMed:25770422). {ECO:0000269|PubMed:25770422}.
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DR   EMBL; LC025956; BAR40288.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0E4AZF8; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR007219; Transcription_factor_dom_fun.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF04082; Fungal_trans; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00906; Fungal_trans; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   4: Predicted;
KW   DNA-binding; Metal-binding; Nucleus; Zinc.
FT   CHAIN           1..751
FT                   /note="Fusarisetin A cluster transcription factor fsa6"
FT                   /id="PRO_0000441303"
FT   DNA_BIND        38..66
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          107..153
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   751 AA;  84312 MW;  2A955CC321CDFE7D CRC64;
     MADQAQDVRP TEWGPGKTPQ GRARLPSSRP REKPQLSCNL CRRRKLRCDR QRPCSSCAQR
     ELGLSCTYAS DRVLSNGVAH QTRTTTQDRI RHLESLVYDL MQNSSANVNA QDQVGATPSP
     RGQPRGPDYP TPAAVHAPST NEEPVSAAVS PADYGSMQST GGGANYVGSA HWAAVLDGIA
     ELKDHLDNEE SHHSDSQGVD PPCPQVTGPQ LLYGCPKPAD KDEILSSIPA RSVVDRLVSR
     YFNSFEMSPA VLHSVQFLKE YEAFWEDPQT TSPIWLGLLF TIMCLATQFE KSRLDPGVQS
     PAVLSMEREL QEMVDTFRLR IPQCLVLGSY AKGGPFVLET LMLYIAAEIF LSSDAEIEIW
     ILMGNTVQLA LHMGYHRDPK HFKGLSPFAA EMRRRIWATI VEMDLGLSAQ MGLPRMVKHW
     QTDTQEPSNL QDSDFDSATV EMPPSRLNTD LTPILYRLVK ARLMTTIGYI WDFSADVRPY
     PYTEVQKMDD KLDLARKSIP ECLKWHSMAR NITDSPQHIM QKVILETVFY RAKIVLHRKY
     MFLPLAQSAS SRRIVLESAL KLLDYQHMLQ EETQPFCQLY QERWRVSSLV NHDFLLATSI
     LCYYLQHAWG ATQRVSESDS FDETIMASLR RSHDIWLQSS NSSKEARKVV RALAVVLGRV
     NTPSADSVGE AGLVFGLPST YPPSTTNDYS QETPGGLGSQ FPMFNSALMP NWATFADDLI
     SAPMITPTAE WQEMDETVDA MGSLNWPWNL Q