ID   FSDG_FUSHE              Reviewed;         509 AA.
AC   S0AU91;
DT   30-AUG-2017, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2013, sequence version 1.
DT   25-MAY-2022, entry version 20.
DE   RecName: Full=MFS transporter fsdG {ECO:0000303|PubMed:15724180};
DE   AltName: Full=Fusaridione A biosynthesis protein G {ECO:0000303|PubMed:15724180};
GN   Name=fsdG {ECO:0000303|PubMed:15724180};
GN   Synonyms=eqi6 {ECO:0000303|PubMed:15724180};
OS   Fusarium heterosporum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium heterosporum species complex.
OX   NCBI_TaxID=42747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 74349 / MF6069;
RX   PubMed=15724180; DOI=10.1039/b413523g;
RA   Sims J.W., Fillmore J.P., Warner D.D., Schmidt E.W.;
RT   "Equisetin biosynthesis in Fusarium heterosporum.";
RL   Chem. Commun. (Camb.) 2:186-188(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND PATHWAY.
RC   STRAIN=ATCC 74349 / MF6069;
RX   PubMed=23614392; DOI=10.1021/cb400159f;
RA   Kakule T.B., Sardar D., Lin Z., Schmidt E.W.;
RT   "Two related pyrrolidinedione synthetase loci in Fusarium heterosporum ATCC
RT   74349 produce divergent metabolites.";
RL   ACS Chem. Biol. 8:1549-1557(2013).
CC   -!- FUNCTION: Efflux pump that might be required for efficient secretion of
CC       fusaridione A or other secondary metabolies produced by the fusaridione
CC       A gene cluster (PubMed:23614392). {ECO:0000305|PubMed:23614392}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AY700570; AGO65989.1; -; Genomic_DNA.
DR   AlphaFoldDB; S0AU91; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Glycoprotein; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..509
FT                   /note="MFS transporter fsdG"
FT                   /id="PRO_0000441311"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        195..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        222..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        298..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        341..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        380..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        408..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        442..462
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        474..494
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        8
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        26
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        189
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        367
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ   SEQUENCE   509 AA;  55704 MW;  BF85E0A3B2F4B094 CRC64;
     MKGNEFRNQT QTTIKNELAE WSDNSNNSQV DYASNAPSGD HVLVDWDGPN DPKNPKNWPH
     SAFLIHTILV SMLCLAGNLA TTMYAPGAAQ LAVEFKTRDT TTIALTVSIY LLGFALAPMV
     TSPLSEVYGR LIVYHTSNIF FLGFNLACAF SSNIGMFIAF RFLAGCAGSA PMTVGGGTIA
     DFAASPEKNN TALRLFALGP LLGPVIGPIV GGFVAENIGW RWTFRIMSIV IAVLSILSCI
     FLRETSAAAI LGRRGARITK ETGKPFMIPG PMPGMPPKPQ QPTKEIVSRS LVRPMKMLIF
     LPQVLILSFY TAFVFGLIYL LFTTFPAVFE GQYGFSPGVS GLSYIGIGFG MVGALFLFNF
     INMKMSNRTD KHGQLIPESY LPLMTWFSPL LPIGFFWYGW SADKQTHWVV PILGTFFVGF
     GSFAIIMPTT AYLVYAQGPQ GAASVLAASN MMRYVFAAFL PLAGQNMYDQ LGLGWGNSLL
     GFLCVVLAPV PAIFQRYGHY LRERFPTEF