ID   FSIP1_RAT               Reviewed;         438 AA.
AC   Q66H16;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Fibrous sheath-interacting protein 1;
GN   Name=Fsip1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-71; SER-88 AND SER-89, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- SIMILARITY: Belongs to the FSIP1 family. {ECO:0000305}.
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DR   EMBL; BC082080; AAH82080.1; -; mRNA.
DR   RefSeq; NP_001013096.1; NM_001013078.1.
DR   AlphaFoldDB; Q66H16; -.
DR   SMR; Q66H16; -.
DR   STRING; 10116.ENSRNOP00000007808; -.
DR   iPTMnet; Q66H16; -.
DR   PhosphoSitePlus; Q66H16; -.
DR   PaxDb; Q66H16; -.
DR   GeneID; 296074; -.
DR   KEGG; rno:296074; -.
DR   UCSC; RGD:1306874; rat.
DR   CTD; 161835; -.
DR   RGD; 1306874; Fsip1.
DR   VEuPathDB; HostDB:ENSRNOG00000005888; -.
DR   eggNOG; ENOG502RXFB; Eukaryota.
DR   HOGENOM; CLU_031884_1_0_1; -.
DR   InParanoid; Q66H16; -.
DR   OMA; PCKVETA; -.
DR   OrthoDB; 608640at2759; -.
DR   PhylomeDB; Q66H16; -.
DR   TreeFam; TF351151; -.
DR   PRO; PR:Q66H16; -.
DR   Proteomes; UP000002494; Chromosome 3.
DR   Bgee; ENSRNOG00000005888; Expressed in testis and 14 other tissues.
DR   InterPro; IPR026246; Fsip1.
DR   PANTHER; PTHR22012; PTHR22012; 1.
DR   Pfam; PF15554; FSIP1; 1.
DR   PRINTS; PR02075; FIBSHEATHIP1.
PE   1: Evidence at protein level;
KW   Coiled coil; Phosphoprotein; Reference proteome.
FT   CHAIN           1..438
FT                   /note="Fibrous sheath-interacting protein 1"
FT                   /id="PRO_0000314921"
FT   REGION          1..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          354..390
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          131..157
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        13..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..87
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..103
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        357..390
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         71
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         88
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         89
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
SQ   SEQUENCE   438 AA;  49568 MW;  47361C2C0CC12A30 CRC64;
     MSMDIIKGNL DGISKPASSS RSRPGSRSSN GSLEVLSPEP GPVKIDMVNK LNSGKEGHTS
     DSRVEERRKI SDDEWADNPR STEPAQESSD EDSNLSQPQG TPEHSDDPKL EGTDAVLQNA
     IHKMHRLDKI LAKRRIREKE IKKQGLEMRI KLWEELKSAK NTEDLENDEE LENTKKFLYL
     TSKSAGTAAE PLHCKFEDDL FSVFHTQIPQ ETYENHTEKD FTCDVEKNGP LIKTEKQPFS
     NTEAIEPRSE HSQVFIIRNA EHSQDFIKRN IELAKSSRSP VVMVEGEKKR LDELLKGLED
     TDSGLSSSEG DQCAWLVPGE GYTLAATESQ QLAEIDIKLQ ELSVDSPAVF SLESQSNKGD
     MEHDSNEERN TEPTPGEKIL RDNKEQRDRE SRLRAIDGKL KEINEQVEEC PVITPGKRNE
     RITWRWLLAK ILEPECKV