FSV1_SCHPO
ID FSV1_SCHPO Reviewed; 247 AA.
AC O14222; P78861;
DT 01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 3.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Syntaxin-like protein fsv1;
GN Name=fsv1; ORFNames=SPAC6F12.03c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=PR745;
RX PubMed=9501991; DOI=10.1093/dnares/4.6.363;
RA Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.;
RT "Identification of open reading frames in Schizosaccharomyces pombe
RT cDNAs.";
RL DNA Res. 4:363-369(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [3]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=14575697; DOI=10.1016/j.bbrc.2003.09.179;
RA Takegawa K., Hosomi A., Iwaki T., Fujita Y., Morita T., Tanaka N.;
RT "Identification of a SNARE protein required for vacuolar protein transport
RT in Schizosaccharomyces pombe.";
RL Biochem. Biophys. Res. Commun. 311:77-82(2003).
CC -!- FUNCTION: Involved in vesicle-mediated protein transport between the
CC Golgi and the vacuole. {ECO:0000269|PubMed:14575697}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000269|PubMed:14575697}; Peripheral membrane protein
CC {ECO:0000269|PubMed:14575697}. Prevacuolar compartment membrane
CC {ECO:0000269|PubMed:14575697}; Peripheral membrane protein
CC {ECO:0000269|PubMed:14575697}. Note=Associated with the Golgi and
CC prevacuolar membrane.
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DR EMBL; D89211; BAA13872.1; -; mRNA.
DR EMBL; CU329670; CAB11087.1; -; Genomic_DNA.
DR PIR; T11654; T11654.
DR PIR; T43015; T43015.
DR RefSeq; NP_593289.1; NM_001018719.2.
DR AlphaFoldDB; O14222; -.
DR SMR; O14222; -.
DR BioGRID; 279386; 75.
DR STRING; 4896.SPAC6F12.03c.1; -.
DR iPTMnet; O14222; -.
DR MaxQB; O14222; -.
DR PaxDb; O14222; -.
DR PRIDE; O14222; -.
DR EnsemblFungi; SPAC6F12.03c.1; SPAC6F12.03c.1:pep; SPAC6F12.03c.
DR GeneID; 2542946; -.
DR KEGG; spo:SPAC6F12.03c; -.
DR PomBase; SPAC6F12.03c; fsv1.
DR VEuPathDB; FungiDB:SPAC6F12.03c; -.
DR eggNOG; KOG3202; Eukaryota.
DR HOGENOM; CLU_1062292_0_0_1; -.
DR InParanoid; O14222; -.
DR OMA; AKQYPRC; -.
DR PhylomeDB; O14222; -.
DR PRO; PR:O14222; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000138; C:Golgi trans cisterna; IDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005770; C:late endosome; IDA:PomBase.
DR GO; GO:0031902; C:late endosome membrane; IDA:PomBase.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005802; C:trans-Golgi network; IDA:PomBase.
DR GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0006896; P:Golgi to vacuole transport; IMP:PomBase.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:1905363; P:positive regulation of endosomal vesicle fusion; IMP:PomBase.
DR GO; GO:0097576; P:vacuole fusion; IGI:PomBase.
DR GO; GO:0048278; P:vesicle docking; IBA:GO_Central.
DR GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR InterPro; IPR045242; Syntaxin.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19957; PTHR19957; 1.
DR Pfam; PF05739; SNARE; 1.
DR SMART; SM00397; t_SNARE; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Golgi apparatus; Membrane; Protein transport;
KW Reference proteome; Transport.
FT CHAIN 1..247
FT /note="Syntaxin-like protein fsv1"
FT /id="PRO_0000210268"
FT DOMAIN 159..221
FT /note="t-SNARE coiled-coil homology"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00202"
FT REGION 88..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 27..94
FT /evidence="ECO:0000255"
FT COMPBIAS 93..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 178
FT /note="R -> S (in Ref. 1; BAA13872)"
FT /evidence="ECO:0000305"
FT CONFLICT 193
FT /note="Q -> P (in Ref. 1; BAA13872)"
FT /evidence="ECO:0000305"
FT CONFLICT 214
FT /note="A -> P (in Ref. 1; BAA13872)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 247 AA; 28266 MW; 9CEA51ED447830AB CRC64;
MSNLLLIIDS VSQKIRDRRK LEEFGQNPDE EIESSLKDVR QELQKLNEEQ SRLEKNAQIP
EYRVRESEAF LIRMQRRLES AEEEFEKQRR ASSIPADGTS AFSANPQVAS TNNKLTPLPS
LQKTTSSSEG SDIEMEAMYP VDGNDPDPIN VNVLAQMHQQ MLNEQEESLG GIEASVQRQK
RMGYAMNTEL SEQNVLLDNM NNDADRIERR FDHAKNRLNK VSRKAKQYPR CFIILLLCAL
LLLVASI
