ID   FTCR_BRUA2              Reviewed;         227 AA.
AC   Q2YJF8;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Flagellar transcriptional regulator FtcR;
GN   Name=ftcR; OrderedLocusNames=BAB2_1099;
OS   Brucella abortus (strain 2308).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=359391;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2308;
RX   PubMed=16299333; DOI=10.1128/iai.73.12.8353-8361.2005;
RA   Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A.,
RA   Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT   "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL   Infect. Immun. 73:8353-8361(2005).
CC   -!- FUNCTION: Required for transcription of flagellar genes. {ECO:0000250}.
CC   -!- MISCELLANEOUS: There is no cognate histidine kinase partner identified
CC       so far for FtcR.
CC   -!- CAUTION: Lacks the conserved Asp residue in position 50 usually
CC       required for phosphorylation. {ECO:0000305}.
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DR   EMBL; AM040265; CAJ13265.1; -; Genomic_DNA.
DR   RefSeq; WP_002966643.1; NZ_KN046823.1.
DR   AlphaFoldDB; Q2YJF8; -.
DR   SMR; Q2YJF8; -.
DR   STRING; 359391.BAB2_1099; -.
DR   EnsemblBacteria; CAJ13265; CAJ13265; BAB2_1099.
DR   GeneID; 45054123; -.
DR   KEGG; bmf:BAB2_1099; -.
DR   PATRIC; fig|359391.11.peg.1883; -.
DR   HOGENOM; CLU_1064703_0_0_5; -.
DR   OMA; TEIGAMR; -.
DR   PhylomeDB; Q2YJF8; -.
DR   PRO; PR:Q2YJF8; -.
DR   Proteomes; UP000002719; Chromosome II.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00383; trans_reg_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR039420; WalR-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR48111; PTHR48111; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..227
FT                   /note="Flagellar transcriptional regulator FtcR"
FT                   /id="PRO_0000319613"
FT   DOMAIN          1..116
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        127..226
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01091"
SQ   SEQUENCE   227 AA;  25738 MW;  8F95853C781A7748 CRC64;
     MIVVVDDRDM VTEGYSSWFG REGITTTGFT PTDFDEWVES VPEQDIMAIE AFLIGECADQ
     HRLPARIRER CKAPVIAVND RPSLEHTLEL FQSGVDDVVR KPVHVREILA RINAIRRRAG
     ASATSGADGT QLGPIRVFSD GRDPQINGID FPLPRRERRI LEYLIANRGR RLNKVQIFSA
     IYGIFDSEVE ENVVESHISK LRKKLRGQLG FDPIDSKRFL GYCINIE