ID   FTCR_BRUO2              Reviewed;         227 AA.
AC   A5VW00;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Flagellar transcriptional regulator FtcR;
GN   Name=ftcR; OrderedLocusNames=BOV_A1045;
OS   Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=444178;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25840 / 63/290 / NCTC 10512;
RX   PubMed=19436743; DOI=10.1371/journal.pone.0005519;
RA   Tsolis R.M., Seshadri R., Santos R.L., Sangari F.J., Lobo J.M.,
RA   de Jong M.F., Ren Q., Myers G., Brinkac L.M., Nelson W.C., Deboy R.T.,
RA   Angiuoli S., Khouri H., Dimitrov G., Robinson J.R., Mulligan S.,
RA   Walker R.L., Elzer P.E., Hassan K.A., Paulsen I.T.;
RT   "Genome degradation in Brucella ovis corresponds with narrowing of its host
RT   range and tissue tropism.";
RL   PLoS ONE 4:E5519-E5519(2009).
CC   -!- FUNCTION: Required for transcription of flagellar genes. {ECO:0000250}.
CC   -!- MISCELLANEOUS: There is no cognate histidine kinase partner identified
CC       so far for FtcR.
CC   -!- CAUTION: Lacks the conserved Asp residue in position 50 usually
CC       required for phosphorylation. {ECO:0000305}.
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DR   EMBL; CP000709; ABQ62478.1; -; Genomic_DNA.
DR   RefSeq; WP_006014731.1; NC_009504.1.
DR   AlphaFoldDB; A5VW00; -.
DR   SMR; A5VW00; -.
DR   EnsemblBacteria; ABQ62478; ABQ62478; BOV_A1045.
DR   GeneID; 45126402; -.
DR   KEGG; bov:BOV_A1045; -.
DR   HOGENOM; CLU_1064703_0_0_5; -.
DR   OMA; TEIGAMR; -.
DR   PhylomeDB; A5VW00; -.
DR   Proteomes; UP000006383; Chromosome II.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00383; trans_reg_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR039420; WalR-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR48111; PTHR48111; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..227
FT                   /note="Flagellar transcriptional regulator FtcR"
FT                   /id="PRO_0000319615"
FT   DOMAIN          1..116
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        127..226
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01091"
SQ   SEQUENCE   227 AA;  25832 MW;  9F948D96CA13D19B CRC64;
     MIVVVDDRDM VTEGYSSWFG REGITTTGFT PTDFDEWVES VPEQDIMAIE AFLIGECADQ
     HRLPARIRER CKAPVIAVND RPSLEHTLEL FQFGVDDVVR KPVHVREILA RINAIRRRAG
     ASATSGADGT QLGPIRVFSD GRDPQINGID FPFPRRERRI LEYLIANRGR RLNKVQIFSA
     IYGIFDSEVE ENVVESHISK LRKKLRGQLG FDPIDSKRFL GYCINIE