FTCR_BRUSU
ID FTCR_BRUSU Reviewed; 227 AA.
AC Q8FUS8; G0KED8;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Flagellar transcriptional regulator FtcR;
GN Name=ftcR; OrderedLocusNames=BRA1140, BS1330_II1131;
OS Brucella suis biovar 1 (strain 1330).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=204722;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=12271122; DOI=10.1073/pnas.192319099;
RA Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F.,
RA Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J.,
RA Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E.,
RA Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L.,
RA Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
RT "The Brucella suis genome reveals fundamental similarities between animal
RT and plant pathogens and symbionts.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=22038969; DOI=10.1128/jb.06181-11;
RA Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT "Revised genome sequence of Brucella suis 1330.";
RL J. Bacteriol. 193:6410-6410(2011).
CC -!- FUNCTION: Required for transcription of flagellar genes. {ECO:0000250}.
CC -!- MISCELLANEOUS: There is no cognate histidine kinase partner identified
CC so far for FtcR.
CC -!- CAUTION: Lacks the conserved Asp residue in position 50 usually
CC required for phosphorylation. {ECO:0000305}.
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DR EMBL; AE014292; AAN34300.1; -; Genomic_DNA.
DR EMBL; CP002998; AEM20576.1; -; Genomic_DNA.
DR PIR; AD3529; AD3529.
DR RefSeq; WP_002966643.1; NZ_KN046805.1.
DR AlphaFoldDB; Q8FUS8; -.
DR SMR; Q8FUS8; -.
DR EnsemblBacteria; AEM20576; AEM20576; BS1330_II1131.
DR GeneID; 45054123; -.
DR KEGG; bms:BRA1140; -.
DR KEGG; bsi:BS1330_II1131; -.
DR PATRIC; fig|204722.21.peg.221; -.
DR HOGENOM; CLU_1064703_0_0_5; -.
DR OMA; TEIGAMR; -.
DR PhylomeDB; Q8FUS8; -.
DR PRO; PR:Q8FUS8; -.
DR Proteomes; UP000007104; Chromosome II.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR039420; WalR-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR48111; PTHR48111; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; SSF46894; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW DNA-binding; Transcription; Transcription regulation.
FT CHAIN 1..227
FT /note="Flagellar transcriptional regulator FtcR"
FT /id="PRO_0000319616"
FT DOMAIN 1..116
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DNA_BIND 127..226
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 227 AA; 25738 MW; 8F95853C781A7748 CRC64;
MIVVVDDRDM VTEGYSSWFG REGITTTGFT PTDFDEWVES VPEQDIMAIE AFLIGECADQ
HRLPARIRER CKAPVIAVND RPSLEHTLEL FQSGVDDVVR KPVHVREILA RINAIRRRAG
ASATSGADGT QLGPIRVFSD GRDPQINGID FPLPRRERRI LEYLIANRGR RLNKVQIFSA
IYGIFDSEVE ENVVESHISK LRKKLRGQLG FDPIDSKRFL GYCINIE