ID   FTIP1_ORYSJ             Reviewed;         824 AA.
AC   Q69T22; A0A0P0WYT4; A3BDJ6;
DT   10-OCT-2018, integrated into UniProtKB/Swiss-Prot.
DT   10-OCT-2018, sequence version 2.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=FT-interacting protein 1 {ECO:0000303|PubMed:28254780};
DE            Short=OsFTIP1 {ECO:0000303|PubMed:28254780};
GN   Name=FTIP1 {ECO:0000303|PubMed:28254780};
GN   OrderedLocusNames=Os06g0614000 {ECO:0000312|EMBL:BAF19989.1},
GN   LOC_Os06g41090 {ECO:0000305};
GN   ORFNames=OsJ_21968 {ECO:0000312|EMBL:EAZ37635.1},
GN   P0417G12.28 {ECO:0000312|EMBL:BAD35565.1},
GN   P0691E09.4 {ECO:0000312|EMBL:BAD35910.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   FUNCTION, INTERACTION WITH RFT1 AND PI4KG4, TISSUE SPECIFICITY, AND
RP   DISRUPTION PHENOTYPE.
RX   PubMed=28254780; DOI=10.1105/tpc.16.00728;
RA   Song S., Chen Y., Liu L., Wang Y., Bao S., Zhou X., Teo Z.W., Mao C.,
RA   Gan Y., Yu H.;
RT   "OsFTIP1-mediated regulation of florigen transport in rice is negatively
RT   regulated by the ubiquitin-like domain kinase OsUbDKgamma4.";
RL   Plant Cell 29:491-507(2017).
CC   -!- FUNCTION: Involved in the export of the long day-specific flower-
CC       promoting signal (florigen) RFT1 from the phloem companion cells to
CC       sieve elements (PubMed:28254780). Promotes flowering under long days
CC       through the transport of RFT1 from the leaves to the shoot apical
CC       meristem (SAM) (PubMed:28254780). {ECO:0000269|PubMed:28254780}.
CC   -!- SUBUNIT: Interacts with RFT1 and PI4KG4. {ECO:0000269|PubMed:28254780}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000269|PubMed:28254780}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- TISSUE SPECIFICITY: Specifically expressed in the phloem including
CC       companion cells. {ECO:0000269|PubMed:28254780}.
CC   -!- DISRUPTION PHENOTYPE: Delayed flowering phenotype under long day
CC       conditions. {ECO:0000269|PubMed:28254780}.
CC   -!- SIMILARITY: Belongs to the MCTP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD35565.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC       Sequence=BAD35910.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC       Sequence=BAF19989.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC       Sequence=BAS98619.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AP003711; BAD35565.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AP004781; BAD35910.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AP008212; BAF19989.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AP014962; BAS98619.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CM000143; EAZ37635.1; -; Genomic_DNA.
DR   RefSeq; XP_015641342.1; XM_015785856.1.
DR   RefSeq; XP_015641343.1; XM_015785857.1.
DR   AlphaFoldDB; Q69T22; -.
DR   SMR; Q69T22; -.
DR   STRING; 4530.OS06T0614000-01; -.
DR   EnsemblPlants; Os06t0614000-01; Os06t0614000-01; Os06g0614000.
DR   GeneID; 4341529; -.
DR   Gramene; Os06t0614000-01; Os06t0614000-01; Os06g0614000.
DR   KEGG; osa:4341529; -.
DR   eggNOG; ENOG502QR9H; Eukaryota.
DR   HOGENOM; CLU_003762_4_0_1; -.
DR   InParanoid; Q69T22; -.
DR   OrthoDB; 234298at2759; -.
DR   Proteomes; UP000000763; Chromosome 6.
DR   Proteomes; UP000007752; Chromosome 6.
DR   Proteomes; UP000059680; Chromosome 6.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR   GO; GO:0048578; P:positive regulation of long-day photoperiodism, flowering; IMP:UniProtKB.
DR   Gene3D; 2.60.40.150; -; 3.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR013583; PRibTrfase_C.
DR   Pfam; PF00168; C2; 3.
DR   Pfam; PF08372; PRT_C; 1.
DR   SMART; SM00239; C2; 3.
DR   SUPFAM; SSF49562; SSF49562; 3.
DR   PROSITE; PS50004; C2; 3.
PE   1: Evidence at protein level;
KW   Endoplasmic reticulum; Flowering; Membrane; Reference proteome; Repeat;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..824
FT                   /note="FT-interacting protein 1"
FT                   /id="PRO_0000445339"
FT   TRANSMEM        625..645
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        657..677
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        764..784
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          48..170
FT                   /note="C2 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00041"
FT   DOMAIN          217..341
FT                   /note="C2 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00041"
FT   DOMAIN          385..522
FT                   /note="C2 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00041"
SQ   SEQUENCE   824 AA;  92948 MW;  F9CF7087805054D4 CRC64;
     MTMTGGHHHD AHHEDFQLKD TNPLLGEQWP KGAAGPARPA VGGGIAGWLG LEKPSSTYDL
     VEQMFFLYVR VVKAKDLPPN PITGSPMDPY VEVKLGNYKG TTKHYDRRAN PEWDQVFAFS
     KSRVQSNVLE VYLKDKEMLG RDDYVGRVVF DLAEVPTRVP PDSPLAPQWY RLEERRVGGG
     GDGGGLKVRG ELMLAVWIGT QADEAFPEAW HSDAATVRGE GVASVRSKAY VSPKLWYLRV
     NVIEAQDVQP QARGRAPEVF VKAQVGNQIL KTSVVAAPTL NPRWNEDLVF VVAEPFEEQL
     LLTVEDRVTP RKDDLLGRAA LPLALFEKRL DHRPFVQSRW FDLEKFGIGG AIEGETRREL
     RFASRVHVRA CLEGAYHVMD ESTMYISDTR PTARQLWKPP VGVLEVGILG AAGLQPMKNR
     DGRGTTDAYC VAKYGQKWVR TRTMLGTFSP TWNEQYTWEV FDPCTVITIG VFDNNHLGNG
     NGNGNNAGGG GGGSPPARDA RVGKIRIRLS TLETDRVYTH AYPLIVLQPS GVKKMGELRL
     AVRFTCLSLM NMVHLYTQPL LPRMHYLHPF TVTQLDALRY QAMGIVAARL GRAEPPLRRE
     VVEYMLDVES HMWSMRRSKA NFFRAVSLFS GAAAAARWFA DVCHWKNVAT TALVHVLLLI
     LVWYPELILP TVFLYMFMIG LWNYRRRPRH PPHMDTKMSW AEAVHPDELD EEFDTFPTSR
     QQDVVYMRYD RLRSVAGRIQ TVVGDMATQG ERLQSLLGWR DPRATCLFVV FCLVAAVVLY
     VTPFRVVALV AGLYLLRHPR FRSRLPAVPS NFFRRLPSRA DSML