ID   FTRL_METKA              Reviewed;         300 AA.
AC   Q8TX60;
DT   10-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Formylmethanofuran--tetrahydromethanopterin formyltransferase-like protein;
GN   OrderedLocusNames=MK0816;
OS   Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC   Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae;
OC   Methanopyrus.
OX   NCBI_TaxID=190192;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA   Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA   Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT   monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC   -!- SIMILARITY: Belongs to the FTR family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE009439; AAM02029.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TX60; -.
DR   SMR; Q8TX60; -.
DR   STRING; 190192.MK0816; -.
DR   PRIDE; Q8TX60; -.
DR   EnsemblBacteria; AAM02029; AAM02029; MK0816.
DR   KEGG; mka:MK0816; -.
DR   PATRIC; fig|190192.8.peg.858; -.
DR   HOGENOM; CLU_081314_0_0_2; -.
DR   OMA; CGDGYEW; -.
DR   BRENDA; 2.3.1.101; 3274.
DR   Proteomes; UP000001826; Chromosome.
DR   GO; GO:0030270; F:formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity; IEA:InterPro.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.70.520; -; 2.
DR   InterPro; IPR014053; ForMFR_H4MPT_ForTrfase.
DR   InterPro; IPR002770; ForMFR_H4MPT_ForTrfase_C.
DR   InterPro; IPR023447; ForMFR_H4MPT_ForTrfase_fd-like.
DR   InterPro; IPR022667; ForMFR_H4MPT_ForTrfase_N.
DR   Pfam; PF01913; FTR; 1.
DR   Pfam; PF02741; FTR_C; 1.
DR   PIRSF; PIRSF006414; Ftr_formyl_trnsf; 1.
DR   SUPFAM; SSF55112; SSF55112; 2.
PE   3: Inferred from homology;
KW   Reference proteome; Transferase.
FT   CHAIN           1..300
FT                   /note="Formylmethanofuran--tetrahydromethanopterin
FT                   formyltransferase-like protein"
FT                   /id="PRO_0000138127"
SQ   SEQUENCE   300 AA;  32966 MW;  EF08FC68601ADC0E CRC64;
     MVEINGVPVE DTFCEAFKGL YARFIVTAAD ERPLREAAEN VAALPATVFG ESEAGVERWL
     DPEETPDGRP GFVAQMWVEY GDDAVKKLEH ELGKRIRQGV LVRPTTRVFD ACEDPDGYID
     TERPIGRCAD GYEYTDVRFD REMVHVPIMM GEFLIERRLG YAEGVAGGLV WLFCEDVDAA
     LEAGYRAVEA LRDVEGVITP FNVCAAGSKP ETIYPDIGPT TNHPYCPTLR DRILDSKVPE
     GVEAIPEIVI NGVSLDVVKR AIGIAIEAAT EVDGVVKVSA GNFGGKLGDY RIPLRECIRE