ID   FTRV_SPIOL              Reviewed;         174 AA.
AC   P38365;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 2.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Ferredoxin-thioredoxin reductase, variable chain, chloroplastic;
DE            Short=FTR-V;
DE   AltName: Full=Ferredoxin-thioredoxin reductase subunit A;
DE            Short=FTR-A;
DE   Flags: Precursor;
GN   Name=FTRV;
OS   Spinacia oleracea (Spinach).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   Caryophyllales; Chenopodiaceae; Chenopodioideae; Anserineae; Spinacia.
OX   NCBI_TaxID=3562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Gaymard E., Schuermann P.;
RL   Submitted (APR-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Green leaf;
RX   PubMed=8167141; DOI=10.1016/0005-2728(94)90218-6;
RA   Falkenstein E., von Schaewen A., Scheibe R.;
RT   "Full-length cDNA sequences for both ferredoxin-thioredoxin reductase
RT   subunits from spinach (Spinacia oleracea L.).";
RL   Biochim. Biophys. Acta 1185:252-254(1994).
RN   [3]
RP   PROTEIN SEQUENCE OF 63-174.
RC   TISSUE=Leaf;
RX   PubMed=8055915; DOI=10.1111/j.1432-1033.1994.tb19014.x;
RA   Iwadate H., Yano K., Kamo M., Gardet-Salvi L., Schuermann P., Tsugita A.;
RT   "Amino acid sequence of spinach ferredoxin:thioredoxin reductase variable
RT   subunit.";
RL   Eur. J. Biochem. 223:465-471(1994).
RN   [4]
RP   PROTEIN SEQUENCE OF N-TERMINUS, AND PHOSPHORYLATION AT SER-70 AND SER-71.
RX   PubMed=1924273;
RA   Tsugita A., Yano K., Gardet-Salvi L., Schuermann P.;
RT   "Characterization of spinach ferredoxin-thioredoxin reductase.";
RL   Protein Seq. Data Anal. 4:9-13(1991).
CC   -!- FUNCTION: Variable subunit of the ferredoxin-thioredoxin reductase
CC       (FTR), which catalyzes the two-electron reduction of thioredoxins by
CC       the electrons provided by reduced ferredoxin.
CC   -!- SUBUNIT: Heterodimer of subunit A (variable subunit) and subunit B
CC       (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin
CC       and thioredoxin.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
CC   -!- SIMILARITY: Belongs to the ferredoxin thioredoxin reductase alpha
CC       subunit family. {ECO:0000305}.
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DR   EMBL; X78880; CAA55480.1; -; mRNA.
DR   EMBL; X77162; CAA54407.1; -; mRNA.
DR   EMBL; X77163; CAA54408.1; -; mRNA.
DR   PIR; S44200; RDSPTA.
DR   AlphaFoldDB; P38365; -.
DR   SMR; P38365; -.
DR   iPTMnet; P38365; -.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0015979; P:photosynthesis; IEA:InterPro.
DR   InterPro; IPR008990; Elect_transpt_acc-like_dom_sf.
DR   InterPro; IPR004207; Fd_thioredoxin_Rdtase_alpha.
DR   InterPro; IPR044166; FTRV.
DR   PANTHER; PTHR46937; PTHR46937; 1.
DR   Pfam; PF02941; FeThRed_A; 1.
DR   SUPFAM; SSF50090; SSF50090; 1.
PE   1: Evidence at protein level;
KW   Chloroplast; Direct protein sequencing; Oxidoreductase; Phosphoprotein;
KW   Plastid; Transit peptide.
FT   TRANSIT         1..62
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000269|PubMed:1924273,
FT                   ECO:0000269|PubMed:8055915"
FT   CHAIN           63..174
FT                   /note="Ferredoxin-thioredoxin reductase, variable chain,
FT                   chloroplastic"
FT                   /id="PRO_0000021290"
FT   REGION          69..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         70
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:1924273,
FT                   ECO:0000269|PubMed:8055915"
FT   MOD_RES         71
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:1924273,
FT                   ECO:0000269|PubMed:8055915"
FT   VARIANT         56
FT                   /note="A -> E (in A2)"
FT   VARIANT         80
FT                   /note="S -> SS (in A2)"
SQ   SEQUENCE   174 AA;  19075 MW;  BE1F06D460B521F5 CRC64;
     MTTGVAVMSS ATAASTATAT AAATARIPLF LSRNNSSATV CSTLRCRTIT RTRTRARLAI
     CCEVALKSDS STGFDSSSSS PPEEDEELKK NLEKVGCKVK VKSPLKVYHV PKLPEVELTP
     DMVGVIKQYV GFWKGKYISP NYPFKVEYRI DVPDRGSVKL VVHLKEEEFE IIAE