ID   FTSA_BUCAI              Reviewed;         418 AA.
AC   P57309;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Cell division protein FtsA {ECO:0000255|HAMAP-Rule:MF_02033};
GN   Name=ftsA {ECO:0000255|HAMAP-Rule:MF_02033}; OrderedLocusNames=BU213;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- FUNCTION: Cell division protein that is involved in the assembly of the
CC       Z ring. May serve as a membrane anchor for the Z ring.
CC       {ECO:0000255|HAMAP-Rule:MF_02033}.
CC   -!- SUBUNIT: Self-interacts. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_02033}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_02033}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_02033}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_02033}.
CC       Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to
CC       the membrane through a conserved C-terminal amphipathic helix.
CC       {ECO:0000255|HAMAP-Rule:MF_02033}.
CC   -!- SIMILARITY: Belongs to the FtsA/MreB family. {ECO:0000255|HAMAP-
CC       Rule:MF_02033}.
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DR   EMBL; BA000003; BAB12930.1; -; Genomic_DNA.
DR   RefSeq; NP_240044.1; NC_002528.1.
DR   RefSeq; WP_009874171.1; NC_002528.1.
DR   AlphaFoldDB; P57309; -.
DR   SMR; P57309; -.
DR   STRING; 107806.10038895; -.
DR   EnsemblBacteria; BAB12930; BAB12930; BAB12930.
DR   KEGG; buc:BU213; -.
DR   PATRIC; fig|107806.10.peg.225; -.
DR   eggNOG; COG0849; Bacteria.
DR   HOGENOM; CLU_037850_3_2_6; -.
DR   OMA; DGIIRHT; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_02033; FtsA; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR020823; Cell_div_FtsA.
DR   InterPro; IPR003494; SHS2_FtsA.
DR   Pfam; PF02491; SHS2_FTSA; 1.
DR   PIRSF; PIRSF003101; FtsA; 1.
DR   SMART; SM00842; FtsA; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR01174; ftsA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome.
FT   CHAIN           1..418
FT                   /note="Cell division protein FtsA"
FT                   /id="PRO_0000062731"
SQ   SEQUENCE   418 AA;  46676 MW;  55BE9915EF2496E6 CRC64;
     MIISKDRKLV VGLEIGTTKV VTLVGEVLID DNIKIIGFGT CLSKGIDKGK INNLDLIVSC
     IQESINKAEI MADCQITSVY LSLSNKYINC QNEIGIIPIS DDEVTKEDIE HVIHIAQSVQ
     ILNEHHILHV IPQEYSIDQQ YGIKNPIGLS GVRMQVKVHL ITCHQNMARN IIKAVEKCDV
     KVDQVIFSGL ASSKAVLTED ECNLGVCMID IGGGTIDFTI YIDGSIKYSQ VIPYAGNIVT
     SDISYAFSTS RDNAENIKIK YGSVKKPPLG SSKNIDFSDI NCNFQQNLQQ DALIDVIESR
     YVELLSLVQD QIVHLQKKLH KKGEKYELLS GIVLTGGGSN ISCLTDCAEK VFQKKVRVAK
     PFNISGLIEK ITEPCYSTVI GLLHYGKESY INIDKKKKEH SFFEIIFKRI NNWFKKEF