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FTSA_HELPJ
ID   FTSA_HELPJ              Reviewed;         493 AA.
AC   Q9ZKM3;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Cell division protein FtsA {ECO:0000255|HAMAP-Rule:MF_02033};
GN   Name=ftsA {ECO:0000255|HAMAP-Rule:MF_02033}; OrderedLocusNames=jhp_0912;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Cell division protein that is involved in the assembly of the
CC       Z ring. May serve as a membrane anchor for the Z ring.
CC       {ECO:0000255|HAMAP-Rule:MF_02033}.
CC   -!- SUBUNIT: Self-interacts. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_02033}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_02033}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_02033}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_02033}.
CC       Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to
CC       the membrane through a conserved C-terminal amphipathic helix.
CC       {ECO:0000255|HAMAP-Rule:MF_02033}.
CC   -!- SIMILARITY: Belongs to the FtsA/MreB family. {ECO:0000255|HAMAP-
CC       Rule:MF_02033}.
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DR   EMBL; AE001439; AAD06487.1; -; Genomic_DNA.
DR   PIR; C71873; C71873.
DR   RefSeq; WP_000400178.1; NC_000921.1.
DR   AlphaFoldDB; Q9ZKM3; -.
DR   SMR; Q9ZKM3; -.
DR   STRING; 85963.jhp_0912; -.
DR   EnsemblBacteria; AAD06487; AAD06487; jhp_0912.
DR   KEGG; hpj:jhp_0912; -.
DR   eggNOG; COG0849; Bacteria.
DR   OMA; DGIIRHT; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_02033; FtsA; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR020823; Cell_div_FtsA.
DR   InterPro; IPR003494; SHS2_FtsA.
DR   Pfam; PF02491; SHS2_FTSA; 1.
DR   SMART; SM00842; FtsA; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR01174; ftsA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane.
FT   CHAIN           1..493
FT                   /note="Cell division protein FtsA"
FT                   /id="PRO_0000062741"
FT   REGION          434..468
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        438..464
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   493 AA;  54692 MW;  D0340339A8BEA294 CRC64;
     MEHKEIVIGV DIGSRKICAI VAEFKDGILR IIGTAHQDSK EINSKAIKRG RINSLAHASN
     AIKEVINSAK KMAGLNADED RNNPISSFRE SYHPKTKAIV SFSGAYTESI RDVTGVASTK
     DNVVTIDEIN RAINNACAKA GLDNDKHILH ALPYRFTLDK QEVNDPLGMS GTRLEVFIHI
     VYTEKNNIEN LEKIMIQSGV EIENIVINSY AASIATLSND ERELGVACVD MGGETCNLTI
     YSGNSIRYNK YLPVGSHHLT TDLSHMLNTP FPYAEEVKIK YGDLSFESGA ETPSQSVQIP
     TTGSDGHESH IVPLSEIQTI MRERALETFK IIHRSIQDSG FEEHLGGGVV LTGGMALMKG
     IKELARTHFT NYPVRLATPV EKYNIMGMFE DLKDPRFSVV VGLILYKAGG HTNYERDSKG
     IIRYHESDDY IRKAHQSNPT PHIHSSPTER NLSDLKTPSA PLNTAKNDDF LPIKPTEQKG
     FFQNLLDKIS KIF
 
 
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