ID   FTSA_PORGI              Reviewed;         479 AA.
AC   O07827;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2003, sequence version 2.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Cell division protein FtsA {ECO:0000255|HAMAP-Rule:MF_02033};
GN   Name=ftsA {ECO:0000255|HAMAP-Rule:MF_02033}; OrderedLocusNames=PG_0583;
OS   Porphyromonas gingivalis (strain ATCC BAA-308 / W83).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC   Porphyromonas.
OX   NCBI_TaxID=242619;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=381;
RA   Akifusa S., Tamura H., Ansai T., Takehara T.;
RL   Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-308 / W83;
RX   PubMed=12949112; DOI=10.1128/jb.185.18.5591-5601.2003;
RA   Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E.,
RA   Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L.,
RA   Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J.,
RA   Granger D., Tettelin H., Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E.,
RA   Fraser C.M.;
RT   "Complete genome sequence of the oral pathogenic bacterium Porphyromonas
RT   gingivalis strain W83.";
RL   J. Bacteriol. 185:5591-5601(2003).
CC   -!- FUNCTION: Cell division protein that is involved in the assembly of the
CC       Z ring. May serve as a membrane anchor for the Z ring.
CC       {ECO:0000255|HAMAP-Rule:MF_02033}.
CC   -!- SUBUNIT: Self-interacts. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_02033}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_02033}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_02033}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_02033}.
CC       Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to
CC       the membrane through a conserved C-terminal amphipathic helix.
CC       {ECO:0000255|HAMAP-Rule:MF_02033}.
CC   -!- SIMILARITY: Belongs to the FtsA/MreB family. {ECO:0000255|HAMAP-
CC       Rule:MF_02033}.
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DR   EMBL; AB004555; BAA20534.1; -; Genomic_DNA.
DR   EMBL; AE015924; AAQ65770.1; -; Genomic_DNA.
DR   AlphaFoldDB; O07827; -.
DR   SMR; O07827; -.
DR   STRING; 242619.PG_0583; -.
DR   EnsemblBacteria; AAQ65770; AAQ65770; PG_0583.
DR   KEGG; pgi:PG_0583; -.
DR   eggNOG; COG0849; Bacteria.
DR   HOGENOM; CLU_037850_4_0_10; -.
DR   OMA; DGIIRHT; -.
DR   Proteomes; UP000000588; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_02033; FtsA; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR020823; Cell_div_FtsA.
DR   InterPro; IPR003494; SHS2_FtsA.
DR   PIRSF; PIRSF003101; FtsA; 1.
DR   SMART; SM00842; FtsA; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome.
FT   CHAIN           1..479
FT                   /note="Cell division protein FtsA"
FT                   /id="PRO_0000062742"
FT   REGION          417..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        418..454
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        185
FT                   /note="T -> A (in Ref. 1; BAA20534)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        369
FT                   /note="E -> G (in Ref. 1; BAA20534)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        405
FT                   /note="I -> T (in Ref. 1; BAA20534)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        418
FT                   /note="G -> D (in Ref. 1; BAA20534)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        421
FT                   /note="T -> A (in Ref. 1; BAA20534)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        441
FT                   /note="K -> R (in Ref. 1; BAA20534)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        444
FT                   /note="V -> L (in Ref. 1; BAA20534)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        457..479
FT                   /note="Missing (in Ref. 1; BAA20534)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   479 AA;  53909 MW;  199AA473ED8561C9 CRC64;
     MSRMNTIYAV IDLGSWYIRG MVARKMEDGR VSPISFYEEP ANNCIRHGCV HNIDEAAAII
     RRIVNQLNEN LEDNTHITSL YVGVGGQSIA SQEFIVRKAM VPEGEVIRTE HIESLWAEMR
     GASFPDKEVL DVTDPLFYVD GKQEIQAKGV FCHELEARFQ LITARRSVKQ NIRIAIEERL
     GLRLTGILVT PLCEAQVLLS DDELTLGCCY VNIGAGCTSV SIYKNRLLAM LRVLPMGGYN
     VTRDLTSLRL TEQEAENMKL NHVSMINDNK SNGSFRMTFA DKFSEREFRS SEVNRLAKAR
     MDEITANYLN ILRLSGLLED IGAGIILNGG GTKINNYMAA MKKILGEVTP AKIRMDRIDT
     DNAISFIEEH ISTIGLAYKA TQPCTDYITT NLGELVSQIE TKEEIPANDT VQDLFAQGRQ
     TERKENEQRD NTDRQREDTP KQTVKKKEKT GPSFGDKLKG AFIKFGSLFD EDTNQDNNR