ID   FTSA_RHIME              Reviewed;         442 AA.
AC   O30994;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Cell division protein FtsA {ECO:0000255|HAMAP-Rule:MF_02033};
GN   Name=ftsA {ECO:0000255|HAMAP-Rule:MF_02033}; OrderedLocusNames=R02169;
GN   ORFNames=SMc01873;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=9352931; DOI=10.1128/jb.179.21.6788-6797.1997;
RA   Ma X., Sun Q., Wang R., Singh G., Jonietz E.L., Margolin W.;
RT   "Interactions between heterologous FtsA and FtsZ proteins at the FtsZ
RT   ring.";
RL   J. Bacteriol. 179:6788-6797(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: Cell division protein that is involved in the assembly of the
CC       Z ring. May serve as a membrane anchor for the Z ring.
CC       {ECO:0000255|HAMAP-Rule:MF_02033}.
CC   -!- SUBUNIT: Self-interacts. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_02033}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_02033}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_02033}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_02033}.
CC       Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to
CC       the membrane through a conserved C-terminal amphipathic helix.
CC       {ECO:0000255|HAMAP-Rule:MF_02033}.
CC   -!- SIMILARITY: Belongs to the FtsA/MreB family. {ECO:0000255|HAMAP-
CC       Rule:MF_02033}.
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DR   EMBL; AF024660; AAC45823.1; -; Genomic_DNA.
DR   EMBL; AL591688; CAC46748.1; -; Genomic_DNA.
DR   RefSeq; NP_386275.1; NC_003047.1.
DR   RefSeq; WP_010969742.1; NC_003047.1.
DR   AlphaFoldDB; O30994; -.
DR   SMR; O30994; -.
DR   STRING; 266834.SMc01873; -.
DR   EnsemblBacteria; CAC46748; CAC46748; SMc01873.
DR   GeneID; 61603633; -.
DR   KEGG; sme:SMc01873; -.
DR   PATRIC; fig|266834.11.peg.3635; -.
DR   eggNOG; COG0849; Bacteria.
DR   HOGENOM; CLU_037850_3_0_5; -.
DR   OMA; DGIIRHT; -.
DR   Proteomes; UP000001976; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_02033; FtsA; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR020823; Cell_div_FtsA.
DR   InterPro; IPR003494; SHS2_FtsA.
DR   Pfam; PF02491; SHS2_FTSA; 1.
DR   PIRSF; PIRSF003101; FtsA; 1.
DR   SMART; SM00842; FtsA; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR01174; ftsA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome.
FT   CHAIN           1..442
FT                   /note="Cell division protein FtsA"
FT                   /id="PRO_0000062744"
SQ   SEQUENCE   442 AA;  46688 MW;  5982A33B3BFAAB83 CRC64;
     MSLFGSANFG LPRLKPLPSK RSHVVSVLDI GSTKVVCMIG RLTPRAESQI LPGRTHSIEV
     IGIGHQKSRG VKNGVIADLD AVESVVRLAV DAAERMAGLT IDSLIVNVSA GRLQSDVYTA
     TIDLGGQEVE ANDLKKVLAA AGHQSLRTDR AILHSLPTGF SLDGERGIRD PLAMFGDVLG
     VDMHVLTAER PALKNLELCV NRAHLSVEGM VATPYASGLA ALVDDEVELG CAAIDMGGGT
     TTISVFAEGK LVHADAVGLG GHHVTTDLAR GLSTRIEDAE RLKVVHGSAL PNSADERDII
     SVPPIGEDDR DQPTHVPRAL VSRIVRARIE ETLELIRDRI QRSGFSPIVG KRIVLTGGAS
     QLTGLPEAAR RILARNVRIG RPLGVSGLPA AAKGPAFSTA VGLMIYPQVA DLETHAAGSG
     MFSTLGGNSR FARMGQWLKE SF