FTSB_ECOK1
ID FTSB_ECOK1 Reviewed; 103 AA.
AC A1AEU2;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Cell division protein FtsB {ECO:0000255|HAMAP-Rule:MF_00599};
GN Name=ftsB {ECO:0000255|HAMAP-Rule:MF_00599}; OrderedLocusNames=Ecok1_26880;
GN ORFNames=APECO1_3775;
OS Escherichia coli O1:K1 / APEC.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=405955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17293413; DOI=10.1128/jb.01726-06;
RA Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J.,
RA Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.;
RT "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7
RT shares strong similarities with human extraintestinal pathogenic E. coli
RT genomes.";
RL J. Bacteriol. 189:3228-3236(2007).
CC -!- FUNCTION: Essential cell division protein. May link together the
CC upstream cell division proteins, which are predominantly cytoplasmic,
CC with the downstream cell division proteins, which are predominantly
CC periplasmic. {ECO:0000255|HAMAP-Rule:MF_00599}.
CC -!- SUBUNIT: Part of a complex composed of FtsB, FtsL and FtsQ.
CC {ECO:0000255|HAMAP-Rule:MF_00599}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00599}; Single-pass type II membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_00599}. Note=Localizes to the division
CC septum. {ECO:0000255|HAMAP-Rule:MF_00599}.
CC -!- SIMILARITY: Belongs to the FtsB family. {ECO:0000255|HAMAP-
CC Rule:MF_00599}.
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DR EMBL; CP000468; ABJ02182.1; -; Genomic_DNA.
DR RefSeq; WP_000517479.1; NC_008563.1.
DR AlphaFoldDB; A1AEU2; -.
DR SMR; A1AEU2; -.
DR EnsemblBacteria; ABJ02182; ABJ02182; APECO1_3775.
DR GeneID; 67413960; -.
DR KEGG; ecv:APECO1_3775; -.
DR HOGENOM; CLU_134863_5_2_6; -.
DR OMA; YELGMVK; -.
DR Proteomes; UP000008216; Chromosome.
DR GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00599; FtsB; 1.
DR InterPro; IPR023081; Cell_div_FtsB.
DR InterPro; IPR007060; FtsL/DivIC.
DR PANTHER; PTHR37485; PTHR37485; 1.
DR Pfam; PF04977; DivIC; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cell inner membrane; Cell membrane; Coiled coil;
KW Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..103
FT /note="Cell division protein FtsB"
FT /id="PRO_1000025696"
FT TOPO_DOM 1..3
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
FT TRANSMEM 4..21
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
FT TOPO_DOM 22..103
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
FT COILED 31..71
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
SQ SEQUENCE 103 AA; 11621 MW; 93FA05EF6376E737 CRC64;
MGKLTLLLLA ILVWLQYSLW FGKNGIHDYT RVNNDVAAQQ ATNAKLKARN DQLFAEIDDL
NGGQEALEER ARNELSMTRP GETFYRLVPD ASKRAQSAGQ NNR