FTSB_NEIMB
ID FTSB_NEIMB Reviewed; 92 AA.
AC P64161; Q9JR95;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Cell division protein FtsB {ECO:0000255|HAMAP-Rule:MF_00599};
GN Name=ftsB {ECO:0000255|HAMAP-Rule:MF_00599}; OrderedLocusNames=NMB1286;
OS Neisseria meningitidis serogroup B (strain MC58).
OC Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=122586;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MC58;
RX PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E.,
RA Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H.,
RA Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M.,
RA Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V.,
RA Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA Moxon E.R., Rappuoli R., Venter J.C.;
RT "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT MC58.";
RL Science 287:1809-1815(2000).
CC -!- FUNCTION: Essential cell division protein. May link together the
CC upstream cell division proteins, which are predominantly cytoplasmic,
CC with the downstream cell division proteins, which are predominantly
CC periplasmic. {ECO:0000255|HAMAP-Rule:MF_00599}.
CC -!- SUBUNIT: Part of a complex composed of FtsB, FtsL and FtsQ.
CC {ECO:0000255|HAMAP-Rule:MF_00599}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00599}; Single-pass type II membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_00599}. Note=Localizes to the division
CC septum. {ECO:0000255|HAMAP-Rule:MF_00599}.
CC -!- SIMILARITY: Belongs to the FtsB family. {ECO:0000255|HAMAP-
CC Rule:MF_00599}.
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DR EMBL; AE002098; AAF41662.1; -; Genomic_DNA.
DR PIR; E81100; E81100.
DR RefSeq; NP_274306.1; NC_003112.2.
DR RefSeq; WP_002213385.1; NC_003112.2.
DR AlphaFoldDB; P64161; -.
DR SMR; P64161; -.
DR STRING; 122586.NMB1286; -.
DR PaxDb; P64161; -.
DR EnsemblBacteria; AAF41662; AAF41662; NMB1286.
DR GeneID; 61281475; -.
DR GeneID; 66752955; -.
DR KEGG; nme:NMB1286; -.
DR PATRIC; fig|122586.8.peg.1611; -.
DR HOGENOM; CLU_134863_5_2_4; -.
DR OMA; YELGMVK; -.
DR Proteomes; UP000000425; Chromosome.
DR GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR GO; GO:0030428; C:cell septum; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IBA:GO_Central.
DR HAMAP; MF_00599; FtsB; 1.
DR InterPro; IPR023081; Cell_div_FtsB.
DR InterPro; IPR007060; FtsL/DivIC.
DR PANTHER; PTHR37485; PTHR37485; 1.
DR Pfam; PF04977; DivIC; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cell inner membrane; Cell membrane; Coiled coil;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..92
FT /note="Cell division protein FtsB"
FT /id="PRO_0000214450"
FT TOPO_DOM 1..3
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
FT TRANSMEM 4..21
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
FT TOPO_DOM 22..92
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
FT COILED 28..50
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
SQ SEQUENCE 92 AA; 10563 MW; 48F5E3DE7AFE02B6 CRC64;
MKWVTVVLSF ALVCCQYSLW FGKGSIGRNS SLREQIAVQE EKNQTLALRN HSLAAEVYDL
ENGQEAISEI ARVELGYIQD GETFYRLIRH NR
