ID   FTSHL_HELSJ             Reviewed;        1460 AA.
AC   Q2EEX7;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=ATP-dependent zinc metalloprotease FtsH homolog;
GN   Name=ftsH;
OS   Helicosporidium sp. subsp. Simulium jonesii (Green alga).
OG   Plastid; Non-photosynthetic plastid.
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC   Chlorellales; Chlorellaceae; Helicosporidium; unclassified Helicosporidium.
OX   NCBI_TaxID=145475;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16630350; DOI=10.1186/1741-7007-4-12;
RA   de Koning A.P., Keeling P.J.;
RT   "The complete plastid genome sequence of the parasitic green alga,
RT   Helicosporidium sp. is highly reduced and structured.";
RL   BMC Biol. 4:12-12(2006).
CC   -!- SUBCELLULAR LOCATION: Plastid membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- DOMAIN: Lacks the zinc protease domain of other FtsH proteins. Also
CC       much longer in both the N- and C-termini.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. {ECO:0000305}.
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DR   EMBL; DQ398104; ABD33966.1; -; Genomic_DNA.
DR   RefSeq; YP_635917.1; NC_008100.1.
DR   AlphaFoldDB; Q2EEX7; -.
DR   GeneID; 4100435; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042170; C:plastid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 2.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00674; AAA; 1.
PE   3: Inferred from homology;
KW   Membrane; Plastid; Transmembrane; Transmembrane helix.
FT   CHAIN           1..1460
FT                   /note="ATP-dependent zinc metalloprotease FtsH homolog"
FT                   /id="PRO_0000293973"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        674..694
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1460 AA;  172686 MW;  E2C9677C2F0302A0 CRC64;
     MNTSNLDITK KSSVNQRNKE RITYLMIKQK IKLLWNKAQM DAFNSNNYII IKFFKKYTYF
     LNLILKDNDI NSYRTQLKTS FILNSKLTIS LLFILIFVGV EASSILFKEI YNQRAASKYF
     KKLNIQFNNF QYIGYINHLT YKSVPSFLNK EQRIISELFF PKKYGAFSNK KIWDELNCYK
     INKFNEYITI DPLWLFSNKK KYNLINKKKL NSLSNKTTKI ILYESENEEE VNDKNSKENK
     SLLMDEKSIS SSNNIKVKRF DLLIDSEKKD RQLLKVSFQK DDNFSFINNK IFGYYYQQLN
     NYLNIKKEII LAIEKLIFYS IKKKKVNLWV KNEAPLEYQG QPLKLINNRS LKASYLINKL
     TDRSNEKIAV TSKQNKFYFK KSPLEAQRFK NKKKFFIASF WQRFRSFLKE TPYYFDYTNR
     IFSKKKFELL SLNKKKISPK DQTQNQEGYS IYLDKSHDII PFEQINLNNP LGTKGVIYNI
     KSNNKKYYNL FNYRSRPFVI HAGIKKYLRR KKKNSYFRRR KINNISSNTL LKLKKSYTQN
     LKMPVFLNPN QWGFYYSKSL KKNIKNRELI SPLVNLPIAH QREYLYNSKY LPFVFTNLEN
     YNVYLPNLNK NLQNKVNSDI LLKSYTYLPK SVKNKKKYTS VFFNLLKQKI ILPDKLINYY
     QDGNYLKFYF FVSWFLLIEL FSILAFMQIF ISIFYILRKS IGEIIIELMH EVSGHLNNVT
     EDLKSWLPEY FFKEPFEWQF FEASTKSFEN FAEKENLKRF FDPYILALQY TKSNLRLPFF
     NIKLDINILQ KPIKSYKKFK SIVLSNNEKE ELLIKPILLV GPPGTGKTLL VRAIAGEADI
     PVIQFIVNKD SPGFTRELVP EYEKLSKAFE YAKSIAPCIL FFDEMDSLAP KRGGGYFGEN
     AWAEIRLNNN ILPYEFSPLK APEPQKNKMD KFKTKKVKPR GTLLQLLYEC NNLSNEKPIL
     LIGATNRQNE IDPAVIRPGR FSTIYNFSLP NSSERIDFCK FYAAGLSMDK EIPWDYIAKR
     TVGFSPSDIS MLMKESSLYG VLNNTKHTLK SLEHGIDRVL GVSKSYLSTL NISKKNVYNK
     ILHMAYYKVG LTLLPLLFKQ EMPAFIKLWP MQERAIVKQN KLEENIHSSE WDTLATLEQK
     LILRYGGKAA ELLFSYLDKD LSDEGFSELS AGQLFITFLV DYYNHYSRSE PLGIIPTLLK
     KRSSTFWHNY EYNLFEFKNI INGPSNVYKE PLIGFYGIEG AESFYDQKDK AKDILDIKDK
     HAQSLNSYLW WYQYVPKDIF KIWTTSLKNQ KWSRFWLPDP ELSFFNLDFV NAEIYVSELI
     DTLLPTWKFN NQGLRKLNKK TRTVWPQIKF ATHEYIVSCL ILSSLNKAME VLDEHREFLD
     FCVAHLIKEE ILREPDILKN LKRFNLEKYH PKNNLEKDQF KDNKKLNILN KYTIVSRSGG
     LNSRRPFPLW IDVDTITKNN