FTSL_BURPS
ID FTSL_BURPS Reviewed; 109 AA.
AC Q63QJ0;
DT 14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Cell division protein FtsL {ECO:0000255|HAMAP-Rule:MF_00910};
GN Name=ftsL {ECO:0000255|HAMAP-Rule:MF_00910}; OrderedLocusNames=BPSL3032;
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243;
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M.,
RA Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D.,
RA Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A.,
RA Brown N.F., Challis G.L., Cherevach I., Chillingworth T., Cronin A.,
RA Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z.,
RA Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S.,
RA Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M.,
RA Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M.,
RA Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC -!- FUNCTION: Essential cell division protein. May link together the
CC upstream cell division proteins, which are predominantly cytoplasmic,
CC with the downstream cell division proteins, which are predominantly
CC periplasmic. {ECO:0000255|HAMAP-Rule:MF_00910}.
CC -!- SUBUNIT: Part of a complex composed of FtsB, FtsL and FtsQ.
CC {ECO:0000255|HAMAP-Rule:MF_00910}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00910}; Single-pass type II membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_00910}. Note=Localizes to the division
CC septum where it forms a ring structure. {ECO:0000255|HAMAP-
CC Rule:MF_00910}.
CC -!- SIMILARITY: Belongs to the FtsL family. {ECO:0000255|HAMAP-
CC Rule:MF_00910}.
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DR EMBL; BX571965; CAH37044.1; -; Genomic_DNA.
DR RefSeq; WP_004527786.1; NZ_CP009538.1.
DR RefSeq; YP_109628.1; NC_006350.1.
DR AlphaFoldDB; Q63QJ0; -.
DR SMR; Q63QJ0; -.
DR STRING; 272560.BPSL3032; -.
DR EnsemblBacteria; CAH37044; CAH37044; BPSL3032.
DR KEGG; bps:BPSL3032; -.
DR PATRIC; fig|272560.51.peg.2234; -.
DR eggNOG; COG3116; Bacteria.
DR OMA; DWSRLQY; -.
DR Proteomes; UP000000605; Chromosome 1.
DR GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00910; FtsL; 1.
DR InterPro; IPR011922; Cell_div_FtsL.
DR PANTHER; PTHR37479; PTHR37479; 1.
DR Pfam; PF04999; FtsL; 1.
DR TIGRFAMs; TIGR02209; ftsL_broad; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..109
FT /note="Cell division protein FtsL"
FT /id="PRO_0000414555"
FT TOPO_DOM 1..3
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT TRANSMEM 4..21
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT TOPO_DOM 22..109
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
SQ SEQUENCE 109 AA; 11916 MW; 143A977C6E70949C CRC64;
MSRLNIFLLI IVMGCALSVV NSTNQQRQIF IQLQRAQSQE HQLQQDYAQL QYQQSALSKT
SRIEQLATSS LKMQPITTGR TQYLTLSPGA AKAVDVPLPA SAAPTGGAR
