ID   FTSL_FRATT              Reviewed;         116 AA.
AC   Q5NGY0;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Cell division protein FtsL {ECO:0000255|HAMAP-Rule:MF_00910};
GN   Name=ftsL {ECO:0000255|HAMAP-Rule:MF_00910}; OrderedLocusNames=FTT_0696;
OS   Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC   Francisellaceae; Francisella.
OX   NCBI_TaxID=177416;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCHU S4 / Schu 4;
RX   PubMed=15640799; DOI=10.1038/ng1499;
RA   Larsson P., Oyston P.C.F., Chain P., Chu M.C., Duffield M., Fuxelius H.-H.,
RA   Garcia E., Haelltorp G., Johansson D., Isherwood K.E., Karp P.D.,
RA   Larsson E., Liu Y., Michell S., Prior J., Prior R., Malfatti S.,
RA   Sjoestedt A., Svensson K., Thompson N., Vergez L., Wagg J.K., Wren B.W.,
RA   Lindler L.E., Andersson S.G.E., Forsman M., Titball R.W.;
RT   "The complete genome sequence of Francisella tularensis, the causative
RT   agent of tularemia.";
RL   Nat. Genet. 37:153-159(2005).
CC   -!- FUNCTION: Essential cell division protein. May link together the
CC       upstream cell division proteins, which are predominantly cytoplasmic,
CC       with the downstream cell division proteins, which are predominantly
CC       periplasmic. {ECO:0000255|HAMAP-Rule:MF_00910}.
CC   -!- SUBUNIT: Part of a complex composed of FtsB, FtsL and FtsQ.
CC       {ECO:0000255|HAMAP-Rule:MF_00910}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00910}; Single-pass type II membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_00910}. Note=Localizes to the division
CC       septum where it forms a ring structure. {ECO:0000255|HAMAP-
CC       Rule:MF_00910}.
CC   -!- SIMILARITY: Belongs to the FtsL family. {ECO:0000255|HAMAP-
CC       Rule:MF_00910}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ749949; CAG45329.1; -; Genomic_DNA.
DR   RefSeq; WP_003020494.1; NZ_CP010290.1.
DR   RefSeq; YP_169712.1; NC_006570.2.
DR   AlphaFoldDB; Q5NGY0; -.
DR   SMR; Q5NGY0; -.
DR   STRING; 177416.FTT_0696; -.
DR   DNASU; 3191028; -.
DR   EnsemblBacteria; CAG45329; CAG45329; FTT_0696.
DR   GeneID; 60807188; -.
DR   KEGG; ftu:FTT_0696; -.
DR   eggNOG; COG3116; Bacteria.
DR   OMA; VTRFEFK; -.
DR   Proteomes; UP000001174; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00910; FtsL; 1.
DR   InterPro; IPR011922; Cell_div_FtsL.
DR   Pfam; PF04999; FtsL; 1.
DR   TIGRFAMs; TIGR02209; ftsL_broad; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..116
FT                   /note="Cell division protein FtsL"
FT                   /id="PRO_0000414557"
FT   TOPO_DOM        1..24
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT   TOPO_DOM        46..116
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
SQ   SEQUENCE   116 AA;  13663 MW;  C06BD8854358B8E9 CRC64;
     MMLTNRQIRV RLFESLKNSF FKKTVGISFA LLFILLITAF SLIVVRFEYK LQLNEQKNLI
     LEDTRLDEQW SQIVLEYSSL ATPTAVEKFA QKEKMTLPTR KTIGFLNEQK EELNNE