FTSL_HAEIN
ID FTSL_HAEIN Reviewed; 107 AA.
AC P45058;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Cell division protein FtsL {ECO:0000255|HAMAP-Rule:MF_00910};
GN Name=ftsL {ECO:0000255|HAMAP-Rule:MF_00910}; OrderedLocusNames=HI_1131;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- FUNCTION: Essential cell division protein. May link together the
CC upstream cell division proteins, which are predominantly cytoplasmic,
CC with the downstream cell division proteins, which are predominantly
CC periplasmic. {ECO:0000255|HAMAP-Rule:MF_00910}.
CC -!- SUBUNIT: Part of a complex composed of FtsB, FtsL and FtsQ.
CC {ECO:0000255|HAMAP-Rule:MF_00910}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00910}; Single-pass type II membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_00910}. Note=Localizes to the division
CC septum where it forms a ring structure. {ECO:0000255|HAMAP-
CC Rule:MF_00910}.
CC -!- SIMILARITY: Belongs to the FtsL family. {ECO:0000255|HAMAP-
CC Rule:MF_00910}.
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DR EMBL; L42023; AAC22786.1; -; Genomic_DNA.
DR PIR; F64184; F64184.
DR RefSeq; NP_439289.1; NC_000907.1.
DR RefSeq; WP_005647600.1; NC_000907.1.
DR AlphaFoldDB; P45058; -.
DR SMR; P45058; -.
DR STRING; 71421.HI_1131; -.
DR DNASU; 950098; -.
DR EnsemblBacteria; AAC22786; AAC22786; HI_1131.
DR KEGG; hin:HI_1131; -.
DR PATRIC; fig|71421.8.peg.1181; -.
DR eggNOG; COG3116; Bacteria.
DR HOGENOM; CLU_156524_2_0_6; -.
DR OMA; DLWHHKW; -.
DR PhylomeDB; P45058; -.
DR BioCyc; HINF71421:G1GJ1-1164-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IBA:GO_Central.
DR HAMAP; MF_00910; FtsL; 1.
DR InterPro; IPR011922; Cell_div_FtsL.
DR PANTHER; PTHR37479; PTHR37479; 1.
DR Pfam; PF04999; FtsL; 1.
DR TIGRFAMs; TIGR02209; ftsL_broad; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..107
FT /note="Cell division protein FtsL"
FT /id="PRO_0000087375"
FT TOPO_DOM 1..24
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT TOPO_DOM 46..107
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
SQ SEQUENCE 107 AA; 12199 MW; 62DBCB30DAFB7367 CRC64;
MSENNKPRYP LQQILVEDLF SSNKLVVLLL IGILVSAMGT IWITHKTRQL ISENGMLILQ
RQALENEYRN LQVQEATEGD STRVESIAIS TLKMKVVSSE QEVEIRE
