ID   FTSL_SHIFL              Reviewed;         121 AA.
AC   P0AEN7; P22187; Q8KMX6;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Cell division protein FtsL {ECO:0000255|HAMAP-Rule:MF_00910};
GN   Name=ftsL {ECO:0000255|HAMAP-Rule:MF_00910};
GN   OrderedLocusNames=SF0080, S0082;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Essential cell division protein. May link together the
CC       upstream cell division proteins, which are predominantly cytoplasmic,
CC       with the downstream cell division proteins, which are predominantly
CC       periplasmic. {ECO:0000255|HAMAP-Rule:MF_00910}.
CC   -!- SUBUNIT: Part of a complex composed of FtsB, FtsL and FtsQ.
CC       {ECO:0000255|HAMAP-Rule:MF_00910}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00910}; Single-pass type II membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_00910}. Note=Localizes to the division
CC       septum where it forms a ring structure. {ECO:0000255|HAMAP-
CC       Rule:MF_00910}.
CC   -!- SIMILARITY: Belongs to the FtsL family. {ECO:0000255|HAMAP-
CC       Rule:MF_00910}.
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DR   EMBL; AE005674; AAN41745.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP15626.1; -; Genomic_DNA.
DR   RefSeq; NP_706038.1; NC_004337.2.
DR   RefSeq; WP_000625658.1; NZ_WPGW01000007.1.
DR   AlphaFoldDB; P0AEN7; -.
DR   SMR; P0AEN7; -.
DR   STRING; 198214.SF0080; -.
DR   DNASU; 1076512; -.
DR   EnsemblBacteria; AAN41745; AAN41745; SF0080.
DR   EnsemblBacteria; AAP15626; AAP15626; S0082.
DR   GeneID; 1024550; -.
DR   GeneID; 67416156; -.
DR   KEGG; sfl:SF0080; -.
DR   KEGG; sfx:S0082; -.
DR   PATRIC; fig|198214.7.peg.95; -.
DR   HOGENOM; CLU_156524_2_0_6; -.
DR   OMA; DLWHHKW; -.
DR   OrthoDB; 1803426at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00910; FtsL; 1.
DR   InterPro; IPR011922; Cell_div_FtsL.
DR   PANTHER; PTHR37479; PTHR37479; 1.
DR   Pfam; PF04999; FtsL; 1.
DR   TIGRFAMs; TIGR02209; ftsL_broad; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..121
FT                   /note="Cell division protein FtsL"
FT                   /id="PRO_0000087374"
FT   TOPO_DOM        1..34
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT   TRANSMEM        35..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT   TOPO_DOM        58..121
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
SQ   SEQUENCE   121 AA;  13627 MW;  6DD5DF7B2ECB7090 CRC64;
     MISRVTEALS KVKGSMGSHE RHALPGVIGD DLLRFGKLPL CLFICIILTA VTVVTTAHHT
     RLLTAQREQL VLERDALDIE WRNLILEENA LGDHSRVERI ATEKLQMQHV DPSQENIVVQ
     K