ID   FTSL_STAA8              Reviewed;         133 AA.
AC   Q2FZ95;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Cell division protein FtsL {ECO:0000255|HAMAP-Rule:MF_00910};
GN   Name=ftsL {ECO:0000255|HAMAP-Rule:MF_00910};
GN   OrderedLocusNames=SAOUHSC_01144;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
CC   -!- FUNCTION: Essential cell division protein. {ECO:0000255|HAMAP-
CC       Rule:MF_00910}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00910};
CC       Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_00910}.
CC       Note=Localizes to the division septum where it forms a ring structure.
CC       {ECO:0000255|HAMAP-Rule:MF_00910}.
CC   -!- SIMILARITY: Belongs to the FtsL family. {ECO:0000255|HAMAP-
CC       Rule:MF_00910}.
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DR   EMBL; CP000253; ABD30254.1; -; Genomic_DNA.
DR   RefSeq; WP_000257598.1; NZ_LS483365.1.
DR   RefSeq; YP_499686.1; NC_007795.1.
DR   AlphaFoldDB; Q2FZ95; -.
DR   SMR; Q2FZ95; -.
DR   STRING; 1280.SAXN108_1178; -.
DR   EnsemblBacteria; ABD30254; ABD30254; SAOUHSC_01144.
DR   GeneID; 3920704; -.
DR   KEGG; sao:SAOUHSC_01144; -.
DR   eggNOG; COG4839; Bacteria.
DR   HOGENOM; CLU_157825_1_1_9; -.
DR   OMA; MAVEKIY; -.
DR   PRO; PR:Q2FZ95; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00910; FtsL; 1.
DR   InterPro; IPR011922; Cell_div_FtsL.
DR   InterPro; IPR007060; FtsL/DivIC.
DR   Pfam; PF04977; DivIC; 1.
DR   TIGRFAMs; TIGR02209; ftsL_broad; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..133
FT                   /note="Cell division protein FtsL"
FT                   /id="PRO_0000414570"
FT   TOPO_DOM        1..45
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT   TRANSMEM        46..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT   TOPO_DOM        66..133
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
SQ   SEQUENCE   133 AA;  15334 MW;  CB67BF10D3290A48 CRC64;
     MAVEKVYQPY DEQVYNSIPK QQPQTKPEKK TVSRKVVVQL TKFEKVLYIT LITVIAMLSI
     YMLSLKMDAY DTRGKIADLD YKIDKQSSEN SALQSEIKKN SSYERIYEKA KKQGMSLEND
     NVKVVRSNGE AKN