ID   FTSL_STRR6              Reviewed;         105 AA.
AC   Q8DR70;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Cell division protein FtsL {ECO:0000255|HAMAP-Rule:MF_00910};
GN   Name=ftsL {ECO:0000255|HAMAP-Rule:MF_00910}; OrderedLocusNames=spr0303;
OS   Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=171101;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-255 / R6;
RX   PubMed=11544234; DOI=10.1128/jb.183.19.5709-5717.2001;
RA   Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S.,
RA   DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA   Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J.,
RA   Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M.,
RA   McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B.,
RA   Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA   Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R.,
RA   Rosteck P.R. Jr., Skatrud P.L., Glass J.I.;
RT   "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL   J. Bacteriol. 183:5709-5717(2001).
CC   -!- FUNCTION: Essential cell division protein. {ECO:0000255|HAMAP-
CC       Rule:MF_00910}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00910};
CC       Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_00910}.
CC       Note=Localizes to the division septum where it forms a ring structure.
CC       {ECO:0000255|HAMAP-Rule:MF_00910}.
CC   -!- SIMILARITY: Belongs to the FtsL family. {ECO:0000255|HAMAP-
CC       Rule:MF_00910}.
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DR   EMBL; AE007317; AAK99107.1; -; Genomic_DNA.
DR   PIR; E95039; E95039.
DR   PIR; G97909; G97909.
DR   RefSeq; NP_357897.1; NC_003098.1.
DR   RefSeq; WP_000818547.1; NC_003098.1.
DR   AlphaFoldDB; Q8DR70; -.
DR   SMR; Q8DR70; -.
DR   STRING; 171101.spr0303; -.
DR   EnsemblBacteria; AAK99107; AAK99107; spr0303.
DR   GeneID; 60233772; -.
DR   GeneID; 66805532; -.
DR   KEGG; spr:spr0303; -.
DR   PATRIC; fig|171101.6.peg.340; -.
DR   eggNOG; COG4839; Bacteria.
DR   HOGENOM; CLU_155775_1_0_9; -.
DR   OMA; MENKEHQ; -.
DR   Proteomes; UP000000586; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00910; FtsL; 1.
DR   InterPro; IPR011922; Cell_div_FtsL.
DR   TIGRFAMs; TIGR02209; ftsL_broad; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..105
FT                   /note="Cell division protein FtsL"
FT                   /id="PRO_0000414571"
FT   TOPO_DOM        1..24
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT   TOPO_DOM        46..105
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
SQ   SEQUENCE   105 AA;  12206 MW;  BFC3910E516AB830 CRC64;
     MAEKMEKTGQ ILQMQLKRFS RVEKAFYFSI AVTTLIVAIS IIFMQTKLLQ VQNDLTKINA
     QIEEKKTELD DAKQEVNELL RAERLKEIAN SHDLQLNNEN IRIAE