ID   3MGH_WOLTR              Reviewed;         169 AA.
AC   Q5GT31;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=Wbm0254;
OS   Wolbachia sp. subsp. Brugia malayi (strain TRS).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Wolbachieae; Wolbachia; unclassified Wolbachia.
OX   NCBI_TaxID=292805;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TRS;
RX   PubMed=15780005; DOI=10.1371/journal.pbio.0030121;
RA   Foster J., Ganatra M., Kamal I., Ware J., Makarova K., Ivanova N.,
RA   Bhattacharyya A., Kapatral V., Kumar S., Posfai J., Vincze T., Ingram J.,
RA   Moran L., Lapidus A., Omelchenko M., Kyrpides N., Ghedin E., Wang S.,
RA   Goltsman E., Joukov V., Ostrovskaya O., Tsukerman K., Mazur M., Comb D.,
RA   Koonin E., Slatko B.;
RT   "The Wolbachia genome of Brugia malayi: endosymbiont evolution within a
RT   human pathogenic nematode.";
RL   PLoS Biol. 3:599-614(2005).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAW70843.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE017321; AAW70843.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041571549.1; NC_006833.1.
DR   AlphaFoldDB; Q5GT31; -.
DR   SMR; Q5GT31; -.
DR   STRING; 292805.Wbm0254; -.
DR   EnsemblBacteria; AAW70843; AAW70843; Wbm0254.
DR   KEGG; wbm:Wbm0254; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_4_1_5; -.
DR   OrthoDB; 1385409at2; -.
DR   Proteomes; UP000000534; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 2.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase.
FT   CHAIN           1..169
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265070"
SQ   SEQUENCE   169 AA;  19246 MW;  EDE51B975823F208 CRC64;
     MNNEILPRNF YERPTLVVAG ELLGKILKFS NFSGVITEVE AYIGMDDPAC HAARGYTDRT
     SVMFGIPGFS YVYFIYGMYY CLNIVTETEG FPAAVLIRGL KLIEPLKANL SGPGILCKRL
     NITREHNKLD LTISHEFCVY ESHINLDYVC TPRIGISKGK EKFWRFKIF