ID   ALF1_XANAC              Reviewed;         334 AA.
AC   Q8PHB5;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Probable fructose-bisphosphate aldolase class 1;
DE            EC=4.1.2.13;
DE   AltName: Full=Fructose-bisphosphate aldolase class I;
DE            Short=FBP aldolase;
GN   OrderedLocusNames=XAC3344;
OS   Xanthomonas axonopodis pv. citri (strain 306).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Xanthomonas.
OX   NCBI_TaxID=190486;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=306;
RX   PubMed=12024217; DOI=10.1038/417459a;
RA   da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R.,
RA   Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F. Jr.,
RA   Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G.,
RA   Cannavan F., Cardozo J., Chambergo F., Ciapina L.P., Cicarelli R.M.B.,
RA   Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B.,
RA   Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F.,
RA   Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T.,
RA   Leite R.P., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A.,
RA   Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J.,
RA   Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M.,
RA   Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A., Rossi A.,
RA   Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A.,
RA   Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M.,
RA   Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P.;
RT   "Comparison of the genomes of two Xanthomonas pathogens with differing host
RT   specificities.";
RL   Nature 417:459-463(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-
CC         phosphate + dihydroxyacetone phosphate; Xref=Rhea:RHEA:14729,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:57642, ChEBI:CHEBI:59776; EC=4.1.2.13;
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 4/4.
CC   -!- SIMILARITY: Belongs to the class I fructose-bisphosphate aldolase
CC       family. {ECO:0000305}.
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DR   EMBL; AE008923; AAM38187.1; -; Genomic_DNA.
DR   RefSeq; WP_003487259.1; NC_003919.1.
DR   AlphaFoldDB; Q8PHB5; -.
DR   SMR; Q8PHB5; -.
DR   STRING; 190486.XAC3344; -.
DR   PRIDE; Q8PHB5; -.
DR   EnsemblBacteria; AAM38187; AAM38187; XAC3344.
DR   GeneID; 61780064; -.
DR   GeneID; 63992491; -.
DR   GeneID; 66912394; -.
DR   KEGG; xac:XAC3344; -.
DR   eggNOG; COG3588; Bacteria.
DR   HOGENOM; CLU_031243_0_0_6; -.
DR   OMA; DYREMLF; -.
DR   UniPathway; UPA00109; UER00183.
DR   Proteomes; UP000000576; Chromosome.
DR   GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR029768; Aldolase_I_AS.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR000741; FBA_I.
DR   PANTHER; PTHR11627; PTHR11627; 1.
DR   Pfam; PF00274; Glycolytic; 1.
DR   PROSITE; PS00158; ALDOLASE_CLASS_I; 1.
PE   3: Inferred from homology;
KW   Glycolysis; Lyase.
FT   CHAIN           1..334
FT                   /note="Probable fructose-bisphosphate aldolase class 1"
FT                   /id="PRO_0000216915"
SQ   SEQUENCE   334 AA;  36276 MW;  A6A52FB21093122E CRC64;
     MSIEQLAETA QAMVAPGKGI IAIDESTSTI AKRFASVGIE NIEENRRAYR ELLLTTPKLS
     DYISGAILFD ETIRQKTKDG VPFAEYMTAH GIIPGIKVDK GAQPLAGMPG ELVTEGLDGL
     RARLEEYYTL GARFAKWRAV INIGEDIPSG TCIEANSHAL ARYAALCQEQ GLVPMVEPEV
     IMDGSHDIET CYEVTEATLR SLFGALYEQN VVLEGTILKA SMVISGKSCE EQASIEEVAE
     STVMCLKSTV PAILPGIVFL SGGQTDEQST AHLNEMHQLG NLPWPLSFSY GRAMQQAALK
     LWAKDMTGNF AKAQQVIYER AKENGLAALG KWKG