ID   FTSQ_MYCLB              Reviewed;         341 AA.
AC   B8ZQQ2;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Cell division protein FtsQ {ECO:0000255|HAMAP-Rule:MF_00911};
GN   Name=ftsQ {ECO:0000255|HAMAP-Rule:MF_00911}; OrderedLocusNames=MLBr00916;
OS   Mycobacterium leprae (strain Br4923).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=561304;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Br4923;
RX   PubMed=19881526; DOI=10.1038/ng.477;
RA   Monot M., Honore N., Garnier T., Zidane N., Sherafi D., Paniz-Mondolfi A.,
RA   Matsuoka M., Taylor G.M., Donoghue H.D., Bouwman A., Mays S., Watson C.,
RA   Lockwood D., Khamispour A., Dowlati Y., Jianping S., Rea T.H.,
RA   Vera-Cabrera L., Stefani M.M., Banu S., Macdonald M., Sapkota B.R.,
RA   Spencer J.S., Thomas J., Harshman K., Singh P., Busso P., Gattiker A.,
RA   Rougemont J., Brennan P.J., Cole S.T.;
RT   "Comparative genomic and phylogeographic analysis of Mycobacterium
RT   leprae.";
RL   Nat. Genet. 41:1282-1289(2009).
CC   -!- FUNCTION: Essential cell division protein. {ECO:0000255|HAMAP-
CC       Rule:MF_00911}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00911};
CC       Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_00911}.
CC       Note=Localizes to the division septum. {ECO:0000255|HAMAP-
CC       Rule:MF_00911}.
CC   -!- SIMILARITY: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00911}.
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DR   EMBL; FM211192; CAR71011.1; -; Genomic_DNA.
DR   RefSeq; WP_010908023.1; NC_011896.1.
DR   AlphaFoldDB; B8ZQQ2; -.
DR   SMR; B8ZQQ2; -.
DR   EnsemblBacteria; CAR71011; CAR71011; MLBr00916.
DR   KEGG; mlb:MLBr00916; -.
DR   HOGENOM; CLU_047677_1_2_11; -.
DR   OMA; SWPHGIG; -.
DR   OrthoDB; 1270665at2; -.
DR   Proteomes; UP000006900; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0090529; P:cell septum assembly; IEA:InterPro.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00911; FtsQ_subfam; 1.
DR   InterPro; IPR005548; Cell_div_FtsQ/DivIB_C.
DR   InterPro; IPR026579; FtsQ.
DR   InterPro; IPR034746; POTRA.
DR   InterPro; IPR013685; POTRA_FtsQ_type.
DR   Pfam; PF03799; FtsQ; 1.
DR   Pfam; PF08478; POTRA_1; 1.
DR   PROSITE; PS51779; POTRA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..341
FT                   /note="Cell division protein FtsQ"
FT                   /id="PRO_0000414678"
FT   TOPO_DOM        1..126
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00911"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00911"
FT   TOPO_DOM        148..341
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00911"
FT   DOMAIN          151..219
FT                   /note="POTRA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
SQ   SEQUENCE   341 AA;  36364 MW;  0BBDEFD88BD636B9 CRC64;
     MTETDEGAPV NHSATMWAVV GVPPVCGGQP GDSGVVAGTS RALVDAAIIA PVTTLTRDEP
     AQYDRYEFEG PRRRARRERA ERRAAQACAI AIEEARREAK HRIHRQMSSE ANSPKPVARG
     VVRGLKTLFA TVMFSIAGFG LGLALYVTPA MSVRNIVVTG IETVTREEVL DAAGVQLGTP
     LLQINTNQVA DQVAAIRRVA SARAQRQYPS ALRITIVERV PVVVKDFPDG PHLFDCDGVD
     FATAPPPPAL PYIDVGHPGP IDPATKAALV VLLALRPEVV SQVARIAAPS VSSITLILTD
     GRAVIWGSTD RAEEKAEKLA ALLTQPGRTY DVSSPDLPTV K