ID   FTSQ_MYCS2              Reviewed;         333 AA.
AC   A0R014; I7G4M7;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Cell division protein FtsQ {ECO:0000255|HAMAP-Rule:MF_00911};
GN   Name=ftsQ {ECO:0000255|HAMAP-Rule:MF_00911};
GN   OrderedLocusNames=MSMEG_4225, MSMEI_4125;
OS   Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS   smegmatis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=246196;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA   Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA   Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT   "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT   mutations or sequencing errors?";
RL   Genome Biol. 8:R20.1-R20.9(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=18955433; DOI=10.1101/gr.081901.108;
RA   Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA   Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT   "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT   and a new MS-based protocol.";
RL   Genome Res. 19:128-135(2009).
CC   -!- FUNCTION: Essential cell division protein. {ECO:0000255|HAMAP-
CC       Rule:MF_00911}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00911};
CC       Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_00911}.
CC       Note=Localizes to the division septum. {ECO:0000255|HAMAP-
CC       Rule:MF_00911}.
CC   -!- SIMILARITY: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00911}.
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DR   EMBL; CP000480; ABK73553.1; -; Genomic_DNA.
DR   EMBL; CP001663; AFP40582.1; -; Genomic_DNA.
DR   RefSeq; WP_011729654.1; NZ_SIJM01000003.1.
DR   RefSeq; YP_888502.1; NC_008596.1.
DR   AlphaFoldDB; A0R014; -.
DR   SMR; A0R014; -.
DR   STRING; 246196.MSMEI_4125; -.
DR   PRIDE; A0R014; -.
DR   EnsemblBacteria; ABK73553; ABK73553; MSMEG_4225.
DR   EnsemblBacteria; AFP40582; AFP40582; MSMEI_4125.
DR   GeneID; 66735570; -.
DR   KEGG; msg:MSMEI_4125; -.
DR   KEGG; msm:MSMEG_4225; -.
DR   PATRIC; fig|246196.19.peg.4145; -.
DR   eggNOG; COG1589; Bacteria.
DR   OMA; SWPHGIG; -.
DR   OrthoDB; 1270665at2; -.
DR   Proteomes; UP000000757; Chromosome.
DR   Proteomes; UP000006158; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0090529; P:cell septum assembly; IEA:InterPro.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00911; FtsQ_subfam; 1.
DR   InterPro; IPR005548; Cell_div_FtsQ/DivIB_C.
DR   InterPro; IPR026579; FtsQ.
DR   InterPro; IPR034746; POTRA.
DR   InterPro; IPR013685; POTRA_FtsQ_type.
DR   Pfam; PF03799; FtsQ; 1.
DR   Pfam; PF08478; POTRA_1; 1.
DR   PROSITE; PS51779; POTRA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..333
FT                   /note="Cell division protein FtsQ"
FT                   /id="PRO_0000414679"
FT   TOPO_DOM        1..118
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00911"
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00911"
FT   TOPO_DOM        140..333
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00911"
FT   DOMAIN          143..211
FT                   /note="POTRA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   REGION          1..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..57
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..99
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   333 AA;  35307 MW;  6A3A9DA56FAA6ACD CRC64;
     MTGTGPHGDP AEDPAGPDDT AAETDGPAEP TEPVDASEAE MTDTTETTAQ TGTTAEADAS
     EEFEGPRRRA RRERAERRAA RDRAMAIEQA RREAKRRAVA GALDPTKSVP RNTIRGLKVL
     MWAALVSVLA VALGLLLYFT PIMSARNVEV SGLAEIPQEE VLTAAAVAPG TPLLQVDTDA
     VAERVATIRR VATARVQREY PSTLKISIVE RVPVVVKDYP DGPHLFDRDG VDFATGPAPL
     ALPYLDADNP GPNDPATRAA LDVMMALPPD VAAQVGRIAA PSVASITLTL IDGRVVVWGT
     DDRTQEKALK LAALLTQPGT TYDVSSPDLP TVK